Results 101 to 110 of about 282,596 (287)

Pengaruh Pemberian Ekstrak Etanol Daun Buas-buas (Premna Cordifolia. Linn) Terhadap Kadar Mda Tikus Wistar Jantan Pasca Paparan Asap Rokok [PDF]

, 2014
Free radical from cigarrete smoke can cause lipid peroxidation that could lead to tissue damage. Tissue damage can be identified by increased levels of MDA (Malondialdehyde). Leavesof buas-buas (Premna cordifolia.
Adyttia, A. (Asri), Untari, E. K. (Eka), Wahdaningsih, S. (Sri)   +2 more
core  

A multipart phase 1 study of the safety, pharmacodynamics and pharmacokinetics of ALG‐055009, a novel thyroid hormone receptor beta (THR‐β) agonist for metabolic dysfunction‐associated steatohepatitis (MASH), in healthy participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract ALG–055009 is an oral thyroid hormone receptor beta (THR‐β) agonist being evaluated for treating metabolic dysfunction–associated steatohepatitis (MASH). This study evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of ALG‐055009 and bioavailability/food effect.
Hakim Charfi, Benedetta Massetto, Megan Fitzgerald, Kha Le, Stanley Wang, Ifong Kan‐Eng, Meenakshi Venkatraman, Naqvi Mohammad, Lawrence Blatt, Tse‐I Lin, Sushmita M. Chanda, John Fry   +11 more
wiley   +1 more source

Cytopathologic Features of Metastatic Malignant Mesothelioma With SMARCB1 (INI‐1) Deficient Diagnosed by Ultrasound‐Guided Fine‐Needle Aspiration: A Case Report

Diagnostic Cytopathology, EarlyView.
ABSTRACT Malignant mesothelioma (MM) is a rare yet aggressive neoplasm that arises from mesothelial cells lining the thoracic and abdominal cavities, the pericardium, and the tunica testis. Characterized by rapid progression, high invasiveness, and a poor prognosis, MM poses significant clinical challenges. SMARCB1, also referred to as INI‐1, hSNF5, or
Jun Yang, Juandi Liu, Jing Jin, Deng Pan, Lei Shao   +4 more
wiley   +1 more source

A comparative study on the protective effects of ascorbic acid and tualang honey on the skin flap of reverse sural fasciocutaneous flap in a smoking rabbit model [PDF]

, 2015
Lower limb traumas impose a great challenge for reconstructive surgeons. Complexity in the tissue constituent of lower limb and the concern regarding vascularity has been the barrier in the process of reconstruction.
Mohd Hussain, Mohd Shakir Bathusha
core  

Rapid Identification of New Psychoactive Substances in Letters by LA‐APCI‐MS

Drug Testing and Analysis, EarlyView.
Laser ablation coupled to molecular mass spectrometry utilizing a modified atmospheric pressure chemical ionization source was used for the detection of synthetic cannabinoid receptor agonists in infused prison mail samples. ABSTRACT New psychoactive substances (NPS), especially synthetic cannabinoid receptor agonists (SCRA), are increasingly smuggled ...
Mark Wesner, Hannah Rämisch, Laura Besch, Johannes Schmeinck, Uwe Karst   +4 more
wiley   +1 more source

Oxidative Stress, Cell Death, and Other Damage to Alveolar Epithelial Cells Induced by Cigarette Smoke

Tobacco Induced Diseases, 2003
Cigarette smoking is a major risk factor in the development of various lung diseases, including pulmonary emphysema, pulmonary fibrosis, and lung cancer.
K. Aoshiba, A. Nagai
doaj   +1 more source

Machine learning‐based prediction of elevated N terminal pro brain natriuretic peptide among US general population

ESC Heart Failure, Volume 12, Issue 2, Page 859-868, April 2025.
Abstract Aims Natriuretic peptide‐based pre‐heart failure screening has been proposed in recent guidelines. However, an effective strategy to identify screening targets from the general population, more than half of which are at risk for heart failure or pre‐heart failure, has not been well established.
Yuichiro Mori, Shingo Fukuma, Kyohei Yamaji, Atsushi Mizuno, Naoki Kondo, Kosuke Inoue   +5 more
wiley   +1 more source

Cigarette smoke induces β₂-integrin-dependent neutrophil migration across human endothelium

Respiratory Research, 2011
Background Cigarette smoking induces peripheral inflammatory responses in all smokers and is the major risk factor for neutrophilic lung disease such as chronic obstructive pulmonary disease.
Garssen Johan, Georgiou Niki A, Kamp Vera M, Kleinjan Marije, Henricks Paul A J, Braber Saskia, Overbeek Saskia A, Kraneveld Aletta D, Folkerts Gert   +8 more
doaj   +1 more source

Pengaruh Ekstrak Kulit Buah Manggis Garcinia Mangostana L.) Terhadap Kualitas Spermatozoa Tikus Wistar (Rattus Norvegicus) Yang Dipapari Asap Rokok [PDF]

, 2016
: Cigarette smoke causes oxidative stress which impact on the quality of spermatozoa. Xanthones in mangosteen rind extract acts as an antioxidant to neutralize free radicals as resistance to oxidative stress.
Rumbajan, J. M. (Janette), Tendean, L. (Lydia), Wuisan, M. (Milary)   +2 more
core  

Cardiovascular toxicity induced by TKIs in patients with chronic myeloid leukaemia: Are women and men different?

ESC Heart Failure, Volume 12, Issue 2, Page 1447-1454, April 2025.
This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.
Cristina Madaudo, Daniela Di Lisi, Antonio Cannatà, Federica Manfrè, Celeste Vullo, Marco Santoro, Ciro Botta, Salvatrice Mancuso, Sergio Siragusa, Alfredo Ruggero Galassi, Giuseppina Novo   +10 more
wiley   +1 more source