Results 51 to 60 of about 231,482 (269)

Elevated liver enzymes is not an impediment to allopurinol dose escalation: an observational cohort study

open access: yesArthritis Care &Research, Accepted Article.
Objective Routine liver enzyme monitoring is advocated while on allopurinol but supporting guidance is lacking. We assessed the incidence and factors associated with elevated liver enzymes in gout patients commenced on allopurinol. Methods 150 patients with gout and normal baseline serum aminotransferases initiated on allopurinol were followed ...
May Shuen Tang   +4 more
wiley   +1 more source

Development of excise rates criteria in the European Union and its member states fulfilment

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2009
European Union regulates member states market to secure free trade. This obtains also in case of excise imposed on cigarettes, which is a composite tax.
Petr David
doaj   +1 more source

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

open access: yesAdvanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer   +12 more
wiley   +1 more source

Ban of single stick cigarettes

open access: yes, 2018
Background and challenges to implementation Sri Lanka implemented FCTC´s Article 11 at 80% from June 2015. Thirasara Foundation in collaboration with Jeewaka Foundation initiated a study in 2016 to monitor the compliance with the PHW printed on tobacco
Sujeewa Dilangana Peiris
core   +1 more source

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

open access: yesAdvanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao   +7 more
wiley   +1 more source

The Use of Electronic Cigarettes for Weight Control Among College Women: A Quantitative Analysis [PDF]

open access: yes, 2021
Introduction. Existing evidence indicates some young adult cigarette smokers are motivated to smoke for weight control. Findings regarding young adult use of e-cigarettes for weight control is limited. As e-cigarettes are most popular among young adults,
Newcombe, Kyra
core  

Curiosity and susceptibility to cigarette smoking among cigarette-naïve, waterpipe smoking US youth: National Youth Tobacco Survey, 2014

open access: yesTobacco Prevention and Cessation, 2017
Introduction Waterpipe smoking is harmful and addictive and can be a gateway to cigarette smoking. This study examined the association between curiosity and susceptibility to cigarette smoking among cigarette-naïve US youth who smoke waterpipe using ...
Raed Bahelah
doaj   +1 more source

A Panel of Circulating Exosomal sncRNAs Associated With Lung Cancer Risk up to 10 Years in Advance

open access: yesAdvanced Science, EarlyView.
Lung cancer is often diagnosed too late, and current screening overlooks many people at risk. In a long‐term study of smokers, a panel of small non‐coding RNAs carried in blood exosomes signals elevated lung cancer risk up to ten years before diagnosis, pointing toward a blood‐based tool for earlier risk detection.
Zhuokun Feng   +12 more
wiley   +1 more source

AARS1‐Mediated RUNX3 K193 Lactylation Enhances the Activation and Cytotoxicity of CD8+T Cells in Smoking‐Related Emphysema

open access: yesAdvanced Science, EarlyView.
Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu   +12 more
wiley   +1 more source

The first Conference on Menthol Cigarettes; setting the research agenda : March 21-22, 2002, Atlanta, GA : executive summary [PDF]

open access: yes
"The First Conference on Menthol Cigarettes was convened in Atlanta, Georgia, on March 21 and 22, 2002. The purpose of the conference was to evaluate the present state of the science concerning the health implications of adding menthol to cigarettes, and

core  

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