Results 101 to 110 of about 164,456 (390)
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Motile cilia are found lining the respiratory and reproductive systems, as well as the brain and spinal column, and the coordinated beat moves fluids over the luminal surfaces.
Shuiqiao Yuan +14 more
semanticscholar +1 more source
The Space Within: How Architected Voids Promote Tissue Formation
Advanced Materials, EarlyView.This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou +3 more
wiley +1 more source
Modelling the Fluid Mechanics of Cilia and Flagella in Reproduction and Development
, 2012 Cilia and flagella are actively bending slender organelles, performing functions such as motility, feeding and embryonic symmetry breaking. We review the mechanics of viscous-dominated microscale flow, including time-reversal symmetry, drag anisotropy of
Blake, John R. +4 more
core +1 more source
Methods and ProtocolsA straightforward whole-mount approach has been developed that uses fluorescence imaging, mouse trachea, and a range of off-the-shelf reagents for rapidly evaluating substance toxicity within the ciliated respiratory epithelium.
Richard Francis
doaj +1 more source
Phosphoinositide lipids in primary cilia biology
Biochemical Journal, 2020 Primary cilia are solitary signalling organelles projecting from the surface of most cell types. Although the ciliary membrane is continuous with the plasma membrane it exhibits a unique phospholipid composition, a feature essential for normal cilia ...
S. Conduit, B. Vanhaesebroeck
semanticscholar +1 more source
ICA treatment diabets induced bone loss via primary cilia/Gli2/Osteocalcin signaling pathway [PDF]
, 2021 Jie Liu +11 more
openalex +1 more source
Physical Intelligence in Small‐Scale Robots and Machines
Advanced Materials, EarlyView.“Physical intelligence” (PI) empowers biological organisms and artificial machines, especially at the small scales, to perceive, adapt, and even reshape their complex, dynamic, and unstructured operation environments. This review summarizes recent milestones and future directions of PI in small‐scale robots and machines.
Huyue Chen, Metin Sitti
wiley +1 more source
Dual and opposing roles of primary cilia in medulloblastoma development. [PDF]
, 2009 Recent work has shown that primary cilia are essential for Hedgehog (Hh) signaling during mammalian development. It is also known that aberrant Hh signaling can lead to cancer, but the role of primary cilia in oncogenesis is not known. Cerebellar granule
Alvarez-Buylla, Arturo +5 more
core
Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis [PDF]
, 2013 The small GTP-binding protein Rab8 is known to play an essential role in intracellular transport and cilia formation. We have previously demonstrated that Rab8a is required for localising apical markers in various organisms.
A. Harada +10 more
core +2 more sources
Heterogeneity of radial spoke components in Tetrahymena cilia
Cellular and Molecular Life SciencesRadial spokes, RS1, RS2, and RS3, are T-shaped, multiprotein complexes that transmit regulatory signals from the central apparatus to outer doublet complexes, including dynein arms.
Marta Bicka +9 more
doaj +1 more source