Results 101 to 110 of about 53,416 (270)

Prevalence of Cystic Fibrosis Carrier Status in Chronic Rhinosinusitis Without Nasal Polyp

open access: yes
International Forum of Allergy &Rhinology, EarlyView.
Do‐Yeon Cho   +4 more
wiley   +1 more source

The Heterotaxy Gene CCDC11 Is Important for Cytokinesis via RhoA Regulation

open access: yesCytoskeleton, EarlyView.
ABSTRACT Mutations in CCDC11 (cfap53) have been identified in multiple patients with heterotaxy (Htx), a disorder of left–right (LR) patterning of the internal organs. In Xenopus, depletion of Ccdc11 causes defects in LR patterning, recapitulating the patient phenotype. Upon Ccdc11 depletion, monociliated cells of the Left–Right Organizer (LRO) exhibit
Saurabh S. Kulkarni   +9 more
wiley   +1 more source

Proteomic analysis of multiple primary cilia reveals a novel mode of ciliary development in mammals

open access: yesBiology Open, 2012
Summary Cilia are structurally and functionally diverse organelles, whose malfunction leads to ciliopathies. While recent studies have uncovered common ciliary transport mechanisms, limited information is available on the proteome of cilia, particularly ...
Keishi Narita   +9 more
doaj   +1 more source

Aberrant Cilia [PDF]

open access: bronze, 1931
F. W. Law
openalex   +1 more source

TRiC Is a Structural Component of Mammalian Sperm Axonemes

open access: yesCytoskeleton, EarlyView.
ABSTRACT The TRiC chaperonin is responsible for folding ~5%–10% of the proteome in eukaryotic cells. Our recent cryo‐electron microscopy studies of axonemes from diverse mammalian cell types led to the surprising discovery that a fully assembled TRiC chaperonin is a structural component of mammalian sperm flagella, where it is tethered to the radial ...
Alan Brown   +3 more
wiley   +1 more source

Stepless shape morphing polymer

open access: yesSmartMat, Volume 4, Issue 1, February 2023., 2023
Reversible stepless discretionary morphing polymer is produced by simply training commercial ultrahigh molecular weight polyethylene (UHMWPE) via thermal treatment associated stretching. The key issue is that the crystals of UHMWPE memorize lots of temporary shapes as independent switching phases.
Lei Min   +6 more
wiley   +1 more source

Phosphorylation at the Helm: Kinase‐Mediated Regulation of Primary Cilia Assembly and Disassembly

open access: yesCytoskeleton, EarlyView.
ABSTRACT The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying ...
Andrea Lacigová, Lukáš Čajánek
wiley   +1 more source

The primary cilium as a multiple cellular signaling scaffold in development and disease [PDF]

open access: yesBMB Reports, 2012
Primary cilia, single hair-like appendage on the surface of themost mammalian cells, were once considered to be vestigialcellular organelles for a past century because of their tinystructure and unknown function.
Hyuk Wan Ko*
doaj  

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