Results 101 to 110 of about 53,999 (295)
ABSTRACT Background The pathogenesis of inflammation in eosinophilic chronic rhinosinusitis (ECRS) and non‐eosinophilic chronic rhinosinusitis (NECRS) remains poorly understood. This study aimed to assess immune cell infiltration within the sinonasal microenvironment in these conditions.
Katarzyna Czerwaty+5 more
wiley +1 more source
ABSTRACT Background Particulate matter ⩽2.5 µm in diameter (PM2.5) and its role in chronic rhinosinusitis (CRS) pathogenesis have gained heightened attention. We previously demonstrated that PM2.5 exposure may bias the nasal mucosa in CRS toward a Type 2 inflammatory pathway.
Rory J. Lubner+5 more
wiley +1 more source
The primary cilium as a multiple cellular signaling scaffold in development and disease [PDF]
Primary cilia, single hair-like appendage on the surface of themost mammalian cells, were once considered to be vestigialcellular organelles for a past century because of their tinystructure and unknown function.
Hyuk Wan Ko*
doaj
REACTIVATION OF GLYCERINATED CILIA FROM TETRAHYMENA PYRIFORMIS [PDF]
I. B. Gibbons
openalex +1 more source
Diosgenin ameliorates silica‐induced tuberculosis in rats
Silicosis increases susceptibility to tuberculosis due to impaired macrophage function and oxidative stress. This study demonstrates that diosgenin, a steroidal saponin, significantly inhibits Mycobacterium smegmatis (IC₅₀ = 0.006 μg/mL), reduces lung fibrosis, and restores antioxidant enzyme levels (↑SOD, ↑CAT, ↓MDA) in silica‐exposed rats ...
Williams Asamoah Adu+5 more
wiley +1 more source
Postnatal Dynamic Ciliary ARL13B and ADCY3 Localization in the Mouse Brain
Primary cilia are hair-like structures found on nearly all mammalian cell types, including cells in the developing and adult brain. A diverse set of receptors and signaling proteins localize within cilia to regulate many physiological and developmental ...
Katlyn K. Brewer+5 more
doaj +1 more source
Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies
Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical, and genetic disease mechanisms with a resulting emphasis on ...
Brent L. Fogel+10 more
wiley +1 more source
LOCALIZATION OF ATP
Albert I. Lansing, François Lamy
openalex +1 more source
Microalgae are emerging as sustainable and economical bioresources that can be utilized as bioinks for creating constructs with intriguing functionalities. This review discusses the properties and applications of microalgae, providing a comprehensive review of recent advancements and challenges in 3D‐printed microalgae‐based constructs for various ...
Yiwei Zou+3 more
wiley +1 more source
Cilia of a Distinctive Structure (9 + 0) in Endocrine and other Tissues [PDF]
A Currie, Denys N. Wheatley
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