Results 131 to 140 of about 53,416 (270)

A CDH23 missense variant in Beauceron dogs with non‐syndromic deafness

open access: yesAnimal Genetics, Volume 54, Issue 1, Page 73-77, February 2023., 2023
Abstract Congenital coat‐colour‐related deafness is common among certain canine breeds especially those exhibiting extreme white spotting or merle patterning. We identified a non‐syndromic deafness in Beauceron dogs characterised by a bilateral hearing loss in puppies that is not linked to coat colour. Pedigree analysis suggested an autosomal recessive
Marie Abitbol   +6 more
wiley   +1 more source

Myelin Formation by Oligodendrocytes Is Enhanced Through Laminin‐411 and Its Derived Peptide

open access: yesGlia, EarlyView.
Laminin (LM) α1, α2, and α4 chains are expressed at the myelination stage of oligodendrocyte (OL). LM411 and its E8 fragment enhance OL myelin membrane formation. A4G47 from LM411E8 is a novel peptide that promotes OL myelin formation. ABSTRACT In the central nervous system, oligodendrocytes (OLs) form myelin sheaths that accomplish the efficient ...
Binri Sasaki   +14 more
wiley   +1 more source

Prenatal diagnosis and clinical pregnancy outcome of fetuses with conotruncal defects in a Chinese cohort

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study aimed to explore genetic etiologies of conotruncal defects (CTDs) in fetuses by analyzing the results of different genetic tests and to assess pregnancy outcomes of fetuses with CTD in a Chinese prenatal cohort. Methods A total of 146 fetuses that underwent invasive prenatal genetic testing for CTD at the prenatal ...
Min Li   +5 more
wiley   +1 more source

Sensing Dog Brain Reactions to Smell by AI Speckle Pattern Analysis

open access: yesJournal of Biophotonics, EarlyView.
The setup of our experiment is shown on Labrador, Johny, a canine participant of our research. The schematic of the setup features: green laser, digital camera, source of smell, and computer. Regions of the brain that were tested are highlighted. Note that the hippocampus and amygdala are on both sides of the dog's brain.
Ilana Propp   +5 more
wiley   +1 more source

Coordination of IFT20 With Other IFT Components Is Required for Ciliogenesis

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Intraflagellar transport is a bidirectional transport system essential for ciliogenesis. Using the IFT20 knockout cell lines established in this study, we found that IFT20 deficiency significantly impaired ciliogenesis and reduced cilium length. Further investigation revealed that IFT20 interacted with other IFT proteins and regulated their levels and ...
Weishu Wang   +6 more
wiley   +1 more source

Ciliary length regulation by intraflagellar transport in zebrafish

open access: yeseLife
How cells regulate the size of their organelles remains a fundamental question in cell biology. Cilia, with their simple structure and surface localization, provide an ideal model for investigating organelle size control.
Yi Sun   +4 more
doaj   +1 more source

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