Results 91 to 100 of about 30,212 (250)

The ciliary machinery is repurposed for T cell immune synapse trafficking of LCK [PDF]

, 2018
Upon engagement of the T cell receptor with an antigen-presenting cell, LCK initiates TCR signaling by phosphorylating its activation motifs. However, the mechanism of LCK activation specifically at the immune synapse is a major question.
Castro Sanchez, Patricia, ElMaghloob, Yasmin, Ismail, Shehab, McIlwraith, Michael J., Roda-Navarro, Pedro, Stephen, Louise A., Yelland, Tamas   +6 more
core   +1 more source

Bio‐Inspired Strategy for Radiation‐Based Thermal Management and Utilization

Advanced Science, EarlyView.
Biological organisms have evolved remarkable strategies to manage and exploit thermal radiation. This review explores bio‐inspired systems that mimic these adaptations—such as radiative cooling, thermal regulation, thermal insulation, water harvesting, infrared camouflage, and infrared detection—and highlights their application in thermal management ...
Hyung Rae Kim, Won Bae Han, Se‐Yeon Heo, Yun Su Go, Suk‐Won Hwang, Young Min Song   +5 more
wiley   +1 more source

Propulsion in a viscoelastic fluid

, 2007
Flagella beating in complex fluids are significantly influenced by viscoelastic stresses. Relevant examples include the ciliary transport of respiratory airway mucus and the motion of spermatozoa in the mucus-filled female reproductive tract. We consider
Bird R. B., Bird R. B., Blake J. R., Blake J. R., Bray D., Denton R., Doi M., Dunn P. F., Eliezer N., Eric Lauga, Gelman R. A., Gilboa A., Giordano A. M., Gray J., Gueron S., Gueron S., Hayat T., Ho H. C., James S. L., Katz D. F., Katz D. F., King M., Larson R. G., Larson R. G., Lillehoj E. P., Liron N., Litt M., Litt M., Meyer F. A., Meyer F. A., Ross S. M., Shake M. P., Suarez S. S., Suarez S. S., Suarez S. S., Suarez S. S., Tam P. Y., Tanner R. I., Wolf D. P., Wolf D. P., Wolf D. P., Wolf D. P., Wolf D. P., Yates G. T.   +43 more
core   +1 more source

Cilia at the node of mouse embryos sense fluid flow for left-right determination via Pkd2 [PDF]

, 2012
Unidirectional fluid flow plays an essential role in the breaking of left-right (L-R) symmetry in mouse embryos, but it has remained unclear how the flow is sensed by the embryo.
A. Kawasumi, B. Dworniczak, B. E. Ehrlich, Collignon, Ermakov, G. Sasaki, Gonzalez-Perrett, H. Hamada, H. Sasaki, H. Shiratori, Hirokawa, I. Y. Kuo, J. A. Belo, J. Nakai, K. Shinohara, Koulen, Marques, Marszalek, McGrath, Nauli, Nonaka, P. Pennekamp, Pazour, Pennekamp, Rankin, REYNOLDS, S. Nonaka, S. Yoshiba, Schweickert, Shinohara, Tabin, Tanaka, Tanaka, Y. Asai   +33 more
core   +1 more source

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

Advanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska, Paula Allepuz‐Fuster, Chloé Maurizy, Alexandre Hego, Sandra Ormenese, Quentin Lion, Arnaud Blomme, Pierre Close, Arnaud Lavergne, Latifa Karim, Marc Thiry, Ivan Nemazanyy, Roopesh Krishnankutty, Jair Marques Jr, Alex von Kriegsheim, Nathaniel F. Henneman, Ganna Panasyuk, Kateryna Shostak, Alain Chariot   +18 more
wiley   +1 more source

Reactivation of ethanol-calcium-isolated cilia from Tetrahymena pyriformis [PDF]

, 1967
Cilia isolated from Tetrahymena after ciliary shedding is induced by the addition of CaCl2 or other salts to cells suspended in an ethanol solution (4, 6, 11) have been studied chemically and enzymatically (4, 6, 11, 12, 13), but until now have never ...
Winicur, Sandra
core   +2 more sources

Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies

Annals of Neurology, EarlyView.
Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical, and genetic disease mechanisms with a resulting emphasis on ...
Brent L. Fogel, Thomas Klopstock, David R. Lynch, Francesca Maltecca, Mayank Verma, Berge A. Minassian, Frances M. Platt, Débora Farina Gonçalves, Hélène Puccio, Andreas Roos, Matthis Synofzik   +10 more
wiley   +1 more source

Architected Microalgae‐Based Matter via 3D Printing: Properties, Printing Techniques, and Applications

Advanced NanoBiomed Research, Volume 5, Issue 7, July 2025.
Microalgae are emerging as sustainable and economical bioresources that can be utilized as bioinks for creating constructs with intriguing functionalities. This review discusses the properties and applications of microalgae, providing a comprehensive review of recent advancements and challenges in 3D‐printed microalgae‐based constructs for various ...
Yiwei Zou, Jiuhong Yi, Yunlu Dai, Iek Man Lei   +3 more
wiley   +1 more source

Progress in Biomimetic Microdevices for Anticancer Drug Screening and their Potential for Enhancing In Vivo Efficacy

Advanced NanoBiomed Research, EarlyView.
Biomimetic microdevices are redefining anticancer drug screening by mimicking complex tumor microenvironments. This review highlights advances in microfluidic systems, cell microarrays, and in vivo‐like models, offering new insights into drug efficacy prediction and personalized medicine. The development of effective anticancer drugs remains a critical
Ching‐Te Kuo, Yen‐Tzu Liao, Hsinyu Lee   +2 more
wiley   +1 more source

Abnormal photoreceptor outer segment development and early retinal degeneration in kif3a mutant zebrafish [PDF]

, 2016
Photoreceptors are highly specialized sensory neurons that possess a modified primary cilium called the outer segment. Photoreceptor outer segment formation and maintenance require highly active protein transport via a process known as intraflagellar ...
Akhtar, Alfinito, Avasthi, Bachmann-Gagescu, Baker, Beech, Brockerhoff, Cao, Deacon, Eblimit, Goetz, Huang, Insinna, Insinna, Insinna, Jiang, Jimeno, Jimeno, Kodani, Krock, Lopes, Louie, Makhankov, Marszalek, Marszalek, Muresan, Muresan, Nascimento, Nonaka, Pazour, Ryan, Scholey, Shu, Stearns, Sukumaran, Traverso, Trivedi, Tsujikawa, Tuma, Westerfield, Whitehead, Wolfrum, Yamazaki, Yang, Zhao   +44 more
core   +2 more sources