Results 41 to 50 of about 31,919 (243)

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

Physics of Rheologically-Enhanced Propulsion: Different Strokes in Generalized Stokes [PDF]

, 2013
Shear-thinning is an important rheological property of many biological fluids, such as mucus, whereby the apparent viscosity of the fluid decreases with shear.
Batchelor G. K., Daniel Loghin, David J. Smith, Katz D. F., Shen X., Taylor G. I., Thomas D. Montenegro-Johnson   +6 more
core   +3 more sources

Charge‐Induced Morphing Gels for Bioinspired Actuation

Advanced Functional Materials, EarlyView.
This study introduces a novel electroactive actuation mechanism that enables the gel material to generate substantial and reversible shape‐changing while preserving topological and isochoric (volumetric) equivalence. The resultant morphing behaviors can mimic the movements of muscle‐driven organelles in nature, including cilia‐like beating and ...
Ciqun Xu, Saba Firouznia, Charl F. J. Faul, Majid Taghavi, Jonathan Rossiter   +4 more
wiley   +1 more source

Propulsion in a viscoelastic fluid

, 2007
Flagella beating in complex fluids are significantly influenced by viscoelastic stresses. Relevant examples include the ciliary transport of respiratory airway mucus and the motion of spermatozoa in the mucus-filled female reproductive tract. We consider
Bird R. B., Bird R. B., Blake J. R., Blake J. R., Bray D., Denton R., Doi M., Dunn P. F., Eliezer N., Eric Lauga, Gelman R. A., Gilboa A., Giordano A. M., Gray J., Gueron S., Gueron S., Hayat T., Ho H. C., James S. L., Katz D. F., Katz D. F., King M., Larson R. G., Larson R. G., Lillehoj E. P., Liron N., Litt M., Litt M., Meyer F. A., Meyer F. A., Ross S. M., Shake M. P., Suarez S. S., Suarez S. S., Suarez S. S., Suarez S. S., Tam P. Y., Tanner R. I., Wolf D. P., Wolf D. P., Wolf D. P., Wolf D. P., Wolf D. P., Yates G. T.   +43 more
core   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

Advanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu, Camilla Mussoni, Mateo S. Andrade Mier, Paula Buettner, Nathaly Chicaiza‐Cabezas, Yi‐Yu Robin Dai, Jessica Faber, Maren Fiedler, Zan Lamberger, Xuen Jen Ng, Vanessa Moessler, Anna Rederer, Jonas Roeder, Sabrina Stecher, Katinka Theis, Jeanette Weigelt, Silvia Budday, Gregor Lang, Natascha Schaefer   +18 more
wiley   +1 more source

Physics of Microswimmers - Single Particle Motion and Collective Behavior

, 2014
Locomotion and transport of microorganisms in fluids is an essential aspect of life. Search for food, orientation toward light, spreading of off-spring, and the formation of colonies are only possible due to locomotion.
Elgeti, Jens, Gompper, Gerhard, Winkler, Roland G.   +2 more
core   +1 more source

Development of a Synthetic 3D Platform for Compartmentalized Kidney In Vitro Disease Modeling

Advanced Healthcare Materials, EarlyView.
A fully synthetic, compartmentalized 3D kidney disease model is introduced. The kidney model combines a PEG‐based hydrogel matrix with anisotropic, enzymatically degradable rod‐shaped microgels to spatially arrange a triple co‐culture of key renal epithelial, endothelial, and fibroblast cells.
Ninon Möhl, Daphne Bouwens, Johanna Abele, Aline Hans, Tanja Topic, Daniel Günther, Jitske Jansen, Rafael Kramann, Laura De Laporte   +8 more
wiley   +1 more source

Ciliary contact interactions dominate surface scattering of swimming eukaryotes

, 2012
Interactions between swimming cells and surfaces are essential to many microbiological processes, from bacterial biofilm formation to human fertilization.
Dunkel, Jörn, Goldstein, Raymond E., Kantsler, Vasily, Polin, Marco   +3 more
core   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Generic flow profiles induced by a beating cilium

, 2012
We describe a multipole expansion for the low Reynolds number fluid flows generated by a localized source embedded in a plane with a no-slip boundary condition.
A. Vilfan, A. Vilfan, A.R. Shields, B. Guirao, B.A. Afzelius, C. Brennen, C. Maul, C. Wollin, C.E. Sing, D. Wu, D.J. Smith, D.J. Smith, E. Lauga, E. Lauga, E.M. Gauger, E.M. Purcell, F. Jülicher, G. Kokot, G. Miño, J. Ainley, J. Blake, J. Blake, J. Hussong, J. Kotar, J. Toonder den, J.B. Freund, J.R. Blake, J.R. Colantonio, K. Drescher, M. Vilfan, M. Vilfan, M.T. Downton, N. Coq, N. Darnton, N. Hirokawa, N. Osterman, N. Uchida, N. Uchida, P. Lenz, P. Marmottant, R. Golestanian, R. Johnson, S. Gueron, S. Gueron, S.N. Khaderi, W. Supatto   +45 more
core   +1 more source