Results 61 to 70 of about 30,212 (250)

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

open access: yesAdvanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz   +2 more
wiley   +1 more source

Fractional Burgers Fluid Flow Due to Metachronal Ciliary Motion in an Inclined Tube

open access: yesFrontiers in Physiology, 2019
Cilia-induced flow of fractional Burgers fluid is studied in an inclined tube for both symplectic and antiplectic wave patterns. The solution of the problem is persued under the long wave length limitation.
Amer Bilal Mann   +3 more
doaj   +1 more source

Physics of Rheologically-Enhanced Propulsion: Different Strokes in Generalized Stokes [PDF]

open access: yes, 2013
Shear-thinning is an important rheological property of many biological fluids, such as mucus, whereby the apparent viscosity of the fluid decreases with shear.
Batchelor G. K.   +6 more
core   +3 more sources

Advancing from MOFs and COFs to Functional Macroscopic Porous Constructs

open access: yesAdvanced Materials, EarlyView.
This review study investigates the recent progress and methodologies for manufacturing metal–organic framework (MOF) or covalent–organic framework (COF)‐based 3D structured macroscopic porous constructs with high structural integrity, providing the possibility to control their porosity across dimensions.
Seyyed Alireza Hashemi   +8 more
wiley   +1 more source

Directed Induction of Functional Multi-ciliated Cells in Proximal Airway Epithelial Spheroids from Human Pluripotent Stem Cells

open access: yesStem Cell Reports, 2016
Multi-ciliated airway cells (MCACs) play a role in mucociliary clearance of the lung. However, the efficient induction of functional MCACs from human pluripotent stem cells has not yet been reported.
Satoshi Konishi   +11 more
doaj   +1 more source

A High‐Throughput AngioPlate Platform with Integrated AngioTEER for Modeling and Monitoring Renal Proximal Tubule Injury

open access: yesAdvanced Materials Technologies, EarlyView.
Renal tubular injury is a major contributor to kidney disease, yet remains poorly understood due to the lack of predictive models. This study presents a high‐throughput 3D renal proximal tubule model on the AngioPlate platform integrated with automated TEER measurements (AngioTEER), enabling real‐time monitoring of drug‐induced nephrotoxicity ...
Shravanthi Rajasekar   +13 more
wiley   +1 more source

Multiple cell types in the oviduct express the prolactin receptor

open access: yesFASEB BioAdvances, 2022
Little is known about the physiological role of prolactin in the oviduct. Examining mRNA for all four isoforms of the prolactin receptor (PRLR) in mice by functional oviduct segment and stage of the estrous cycle, we found short form 3 (SF3) to be the ...
Kelly C. Radecki   +6 more
doaj   +1 more source

Collective beating of artificial microcilia

open access: yes, 2011
We combine technical, experimental and theoretical efforts to investigate the collective dynamics of artificial microcilia in a viscous fluid. We take advantage of soft-lithography and colloidal self-assembly to devise microcapets made of hundreds of ...
Antoine Bricard   +8 more
core   +1 more source

Absolute proteomic quantification reveals design principles of sperm flagellar chemosensation [PDF]

open access: yes, 2019
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Troetschel, C., Hamzeh, H., Alvarez, L., Pascal, R., Lavryk, F., Boenigk, W., Koerschen, H.
Alvarez, Luis   +14 more
core   +1 more source

NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea

open access: yesAdvanced Science, EarlyView.
This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi   +16 more
wiley   +1 more source

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