Results 71 to 80 of about 256,965 (211)
Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications
Advanced Science, EarlyView.HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang +5 more
wiley +1 more source
Fractional Burgers Fluid Flow Due to Metachronal Ciliary Motion in an Inclined Tube
Frontiers in Physiology, 2019 Cilia-induced flow of fractional Burgers fluid is studied in an inclined tube for both symplectic and antiplectic wave patterns. The solution of the problem is persued under the long wave length limitation.
Amer Bilal Mann +3 more
doaj +1 more source
Multiple cell types in the oviduct express the prolactin receptor
FASEB BioAdvances, 2022 Little is known about the physiological role of prolactin in the oviduct. Examining mRNA for all four isoforms of the prolactin receptor (PRLR) in mice by functional oviduct segment and stage of the estrous cycle, we found short form 3 (SF3) to be the ...
Kelly C. Radecki +6 more
doaj +1 more source
Rotating magnetic field actuation of a multicilia configuration [PDF]
, 2009 This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009) +3 more
core
Gli2a protein localization reveals a role for Iguana/DZIP1 in primary ciliogenesis and a dependence of Hedgehog signal transduction on primary cilia in the zebrafish [PDF]
, 2010 Background: In mammalian cells, the integrity of the primary cilium is critical for proper regulation of the Hedgehog (Hh) signal transduction pathway.
Ingham, P.W. +3 more
core +3 more sources
HDAC6 and USP9X Control Glutamine Metabolism by Stabilizing GS to Promote Glioblastoma Tumorigenesis
Advanced Science, EarlyView.Glioblastoma (GBM) growth relies on glutamine synthetase (GS), which is stabilized by histone deacetylase 6 (HDAC6) and deubiquitinated by ubiquitin‐specific peptidase 9, X‐linked (USP9X). HDAC6 promotes GS deacetylation, while USP9X removes its K48‐linked polyubiquitination, enhancing GS stability.
Go Woon Kim +9 more
wiley +1 more source
Stem Cell Reports, 2016 Multi-ciliated airway cells (MCACs) play a role in mucociliary clearance of the lung. However, the efficient induction of functional MCACs from human pluripotent stem cells has not yet been reported.
Satoshi Konishi +11 more
doaj +1 more source
Scientific Reports, 2023 The main focus of this article is to mathematically formulate the microfluidics-based mechanical system for nanofluids. A 50:50 mixture of propylene glycol (PG) and water is used as a heat transfer fluid because of its tremendous anti-freezing properties,
Javaria Akram, Noreen Sher Akbar
doaj +1 more source
Asymmetry in cilia configuration induces hydrodynamic phase locking [PDF]
Phys. Rev. E 97, 032411 (2018), 2017 To gain insight into the nature of biological synchronization at the microscopic scale, we here investigate the hydrodynamic synchronization between conically rotating objects termed nodal cilia. A mechanical model of three rotating cilia is proposed with consideration of variation in their shapes and geometrical arrangement.
arxiv +1 more source
Advances in 3D and 4D Printing of Soft Robotics and Their Applications
Advanced Intelligent Systems, EarlyView.This article summarizes the development of 3D‐printed soft robotics in the recent decade. The article discusses the printing capabilities of different additive manufacturing technologies in terms of soft polymers, multimaterial printability, soft robotic printing, and 4D printing.
Hao Liu +5 more
wiley +1 more source