Results 141 to 150 of about 3,437,891 (289)

Iqcm Is Dispensable for Male Fertility in Mice

open access: yesiNew Medicine, EarlyView.
Schematic overview of the experimental workflow. Iqcm is highly expressed in mice testis (left). Iqcm−/− mice were generated via CRISPR/Cas9 (second panel). Phenotypic analyses including testis/epididymis histology (H&E), sperm morphology, and litter size revealed no significant differences between Iqcm+/+ and Iqcm−/− mice (third panel).
Zhaojuan Yu   +6 more
wiley   +1 more source

Combined Karyotyping, Copy Number Variation Sequencing, and Whole Exome Sequencing in the Prenatal Diagnosis of Congenital Heart Disease: Detection Rates and Phenotypic Associations

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study combined karyotyping, copy number variation sequencing, and whole‐exome sequencing to assess the value of genetic testing in the prenatal diagnosis of congenital heart disease (CHD) and to evaluate the relationship between genetic variants and prenatal phenotypes.
Jieqiong Xie   +7 more
wiley   +1 more source

Histopathological Changes After Standard and Novel Endoscopic Cyclophotocoagulation versus Transscleral Cyclophotocoagulation in Human Cadaveric Eyes

open access: yesClinical Ophthalmology
Saif Aldeen Alryalat,1 Cara E Capitena Young,2 Mina B Pantcheva,2 Paula Ender,3 Leonard K Seibold,2 Malik Y Kahook2 1Department of Ophthalmology and Visual Science, University of Illinois Chicago, Chicago, IL, USA; 2Department of Ophthalmology ...
Alryalat SA   +5 more
doaj  

GSK3 Inhibition During Annelid Head Regeneration Results in a Hyper‐Proliferative Blastema and Impaired Differentiation

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
A whole‐body regenerative annelid was treated with a GSK3 inhibitor. While posterior regeneration was mostly normal, GSK3 inhibition prevented differentiation of anterior‐specific structures and instead produced a persistent, oversized, hyper‐proliferative blastema. This suggests that GSK3 promotes anterior identity and halts proliferation during axial
James D. Nowotny   +5 more
wiley   +1 more source

Transillumination - Ciliary Body Neurofibromas

open access: yes, 1986
Example of transillumination on a patient with neurofibromatosis, but without Lisch nodules. Shows suspected neurofibromas in the ciliary body.VBorbitalneurofibroma; EXAMciliary; IC-B4av-iris-ciliary ...
Kathleen B. Digre, MD
core  

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

open access: yesJSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed   +5 more
wiley   +1 more source

Comparison of particle properties and biovolume estimates from FlowCam and microscopy for kettle hole phytoplankton communities

open access: yesLimnology and Oceanography: Methods, EarlyView.
Abstract The integration of high‐throughput image–based flow cytometry into routine phytoplankton assessment requires rigorous evaluation against established microscopy techniques. As method agreement is often site‐ and species‐specific, case‐by‐case validation is essential to successfully adopt emerging methods.
Jasper Münnich   +4 more
wiley   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

open access: yesMed Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng   +14 more
wiley   +1 more source

Quantitative Ciliary Body Imaging Using Image-Registered Swept-Source AS-OCT and Ultrasound Biomicroscopy. [PDF]

open access: yesTransl Vis Sci Technol
Namba M   +7 more
europepmc   +1 more source

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