Results 101 to 110 of about 15,550 (253)

Nitric oxide-induced activation of the AMP-activated protein kinase alpha2 subunit attenuates IKappaB kinase activity and inflammatory responses in endothelial cells [PDF]

, 2011
Background: In endothelial cells, activation of the AMP-activated protein kinase (AMPK) has been linked with anti-inflammatory actions but the events downstream of kinase activation are not well understood.
Beß, Elke, Fißlthaler, Beate, Fleming, Ingrid, Frömel, Timo   +3 more
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Profiling risk factors for chronic uveitis in juvenile idiopathic arthritis: a new model for EHR-based research. [PDF]

, 2013
BackgroundJuvenile idiopathic arthritis is the most common rheumatic disease in children. Chronic uveitis is a common and serious comorbid condition of juvenile idiopathic arthritis, with insidious presentation and potential to cause blindness. Knowledge
Bauer-Mehren, Anna, Cole, Tyler S, Frankovich, Jennifer, Iyer, Srinivasan, Lependu, Paea, Shah, Nigam H   +5 more
core   +3 more sources

Cilostazol Combats Lipopolysaccharide-Induced Hippocampal Injury in Rats: Role of AKT/GSK3β/CREB Curbing Neuroinflammation

Advances in Pharmacological and Pharmaceutical Sciences
Neuroinflammation is important in the pathophysiology of several degenerative brain disorders. This study looked at the potential neuroprotective benefits of cilostazol, a phosphodiesterase inhibitor, against LPS-induced hippocampus damage in rodents and
Doaa Abou El-ezz, Waleed Aldahmash, Tuba Esatbeyoglu, Sherif M. Afifi, Marawan Abd Elbaset   +4 more
doaj   +1 more source

Cilostazol improves endothelial function in acute cerebral ischemia patients: a double-blind placebo controlled trial with flow-mediated dilation technique

BMC Neurology, 2017
Background In order to evaluate the impact of cilostazol on endothelial function, we compared the changes of flow-mediated dilation (FMD) between aspirin and cilostazol groups in patients with acute cerebral ischemia.
Seong-Joon Lee, Jin Soo Lee, Mun Hee Choi, Sung Eun Lee, Dong Hoon Shin, Ji Man Hong   +5 more
doaj   +1 more source

Associations of Weight Change With Changes in Calf Muscle Characteristics and Functional Decline in Peripheral Artery Disease. [PDF]

, 2019
Background Among people with lower extremity peripheral artery disease, obesity is associated with faster functional decline than normal weight. The association of weight loss with functional decline in peripheral artery disease is unknown.
Bazzano, Lydia A, Criqui, Michael H, Ferrucci, Luigi, Guralnik, Jack M, Kibbe, Melina R, Leeuwenburgh, Christiaan, McDermott, Mary M, Polonsky, Tamar S, Sufit, Robert L, Tian, Lu, Zhang, Dongxue   +10 more
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Thrombin-anti-thrombin levels and patency of arterio-venous fistula in patients undergoing haemodialysis compared to healthy volunteers : a prospective analysis [PDF]

, 2013
Peer reviewedPublisher ...
Brittenden, Julie, Fluck, Nicholas, Ford, Isobel, Milburn, James, Mutch, Nicola J   +4 more
core   +2 more sources

Evaluation of antidepressant and anxiolytic activity of phosphodiesterase 3 inhibitor - Cilostazol

Indian Journal of Psychological Medicine, 2012
Background: Cyclic nucleotide Phosphodiesterases (PDEs) are ubiquitously distributed in mammalian tissues and play a major role in cell signaling by hydrolyzing cyclic Adenosine Monophosphate (cAMP) and cyclic Guanosine Monophosphate (cGMP).
Dipesh S Patel, Indermeet Singh Anand, Parloop A Bhatt   +2 more
doaj   +1 more source

The drug risks of cilostazol: A pharmacovigilance study of FDA Adverse Event Reporting System database.

PLoS ONE
ObjectiveCilostazol is indicated for alleviating intermittent claudication (IC) in stable-phase peripheral arterial disease (PAD) patients. Conducting data mining on adverse events (AEs) of cilostazol in the U.S.
Lufeng Peng, Xueli Li, Junhai Li, Shibin Liu, Gang Liang   +4 more
doaj   +1 more source

Benefit of Cilostazol in Patients with High Risk of Bleeding: Subanalysis of Cilostazol Stroke Prevention Study 2 [PDF]

, 2014
Shinichiro Uchiyama, Yukito Shinohara, Yasuo Katayama, Takenori Yamaguchi, Shunnosuke Handa, Kempei Matsuoka, Yasuo Ohashi, Norio Tanahashi, Hiroko Yamamoto, Chokoh Genka, Yasuhisa Kitagawa, Hideo Kusuoka, K Nishimaru, Motoo Tsushima, Yukihiro Koretsune, Tohru Sawada, Chikuma Hamada, for the CSPS 2 group   +17 more
openalex   +1 more source

Síntesis y caracterización de nanopartículas híbridas lípido-polímero cargadas con cilostazol, un inhibidor de la función plaquetaria [PDF]

, 2015
Tesis (Tecnólogo Médico)Las enfermedades cardiovasculares (ECV) son la principal causa de muerte en el mundo y su fisiopatología en gran parte está íntimamente ligada con la formación de placas de ateroma y su consecuente efecto en la activación ...
Bahamonde Norambuena, Daniela Alejandra, Molina Pereira, Álvaro Rodrigo   +1 more
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