Results 11 to 20 of about 4,265 (97)

Gallstones were associated with the gastrointestinal adverse events of cinacalcet in hemodialysis patients with secondary hyperparathyroidism

Renal Failure, 2018
This study aimed to investigate the association of gastrointestinal (GI) adverse events of cinacalcet with gallstones in the hemodialysis (HD) patients with secondary hyperparathyroidism (SHPT).
Keiichi Otsuka, Yoichi Ohno, Joji Oshima
doaj   +1 more source

Development and validation of an LC-MS/MS method by one-step precipitation for cinacalcet in human plasma

Heliyon, 2023
A sensitive, convenient, rapid and economic liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed to determine cinacalcet concentration in human plasma.
Haoyang Lu, Tingting Guo, Shanqing Huang, Yuandan Li, Yuguan Wen, Dewei Shang, Xin Wen   +6 more
doaj   +1 more source

Retrospective Study Looking at Cinacalcet in the Management of Hyperparathyroidism after Kidney Transplantation

Journal of Transplantation, 2017
Objectives. The primary objective of this study is to evaluate the use of cinacalcet in the management of hyperparathyroidism in kidney transplant recipients.
Habib Mawad, Hugues Bouchard, Duy Tran, Denis Ouimet, Jean-Philippe Lafrance, Robert Zoël Bell, Sarah Bezzaoucha, Anne Boucher, Suzon Collette, Vincent Pichette, Lynne Senécal, Michel Vallée   +11 more
doaj   +1 more source

The effect of evocalcet on vagus nerve activity of the gastrointestinal tract in miniature pigs.

PLoS ONE, 2021
Evocalcet is a novel calcimimetic agent with fewer gastrointestinal (GI) adverse effects compared to cinacalcet. Although it is thought that cinacalcet induces GI side effects through the direct stimulation of the calcium receptor (CaR) expressed in the ...
Shin Tokunaga, Takehisa Kawata
doaj   +1 more source

Cost-effectiveness analysis of cinacalcet vs. paricalcitol in the treatment of hyperparathyroidism secondary to chronic kidney disease [PDF]

Brazilian Journal of Nephrology, 2023
Introduction For the reduction of PTH levels, two classes of drugs are available in the Brazilian market: non-selective and selective vitamin D receptor activators and calcimimetics.
Daniela Ponce, Marilia Mastrocolla de Almeida Cardoso, Juliana Rodrigues Machado Rúgolo, Silvana Andrea Molina, Luis Gustavo Modelli de Andrade, Daniel da Silva Pereira Curado   +5 more
doaj   +1 more source

Cinacalcet Treatment of Primary Hyperparathyroidism

International Journal of Endocrinology, 2011
Although parathyroidectomy remains the only curative approach to most primary hyperparathyroidism cases, medical treatment with cinacalcet HCl has been proven to be a reasonable alternative for several patient subgroups. Cinacalcet almost always controls
H. M. Rothe, O. Liangos, P. Biggar, A. Petermann, M. Ketteler   +4 more
doaj   +1 more source

Repurposing calcium-sensing receptor agonist cinacalcet for treatment of CFTR-mediated secretory diarrheas

JCI Insight, 2021
Diarrhea is a major cause of global mortality, and outbreaks of secretory diarrhea such as cholera remain an important problem in the developing world.
Apurva A. Oak, Parth D. Chhetri, Amber A. Rivera, Alan S. Verkman, Onur Cil   +4 more
doaj   +1 more source

Cinacalcet-Associated Resolution of Primary Hyperparathyroidism in a Patient With Normal Kidney Function

Journal of Investigative Medicine High Impact Case Reports, 2020
Cinacalcet use is associated with risk of hypocalcemia; however, this risk has been mostly demonstrated in patients with chronic kidney disease.
Son Nguyen DO, PharmD, Elvira O. Gosmanova MD, Aidar R. Gosmanov MD, PhD, FACE   +2 more
doaj   +1 more source

Cost-effectiveness analysis of cinacalcet for haemodialysis patients with moderate-to-severe secondary hyperparathyroidism in China: evaluation based on the EVOLVE trial

BMJ Open, 2020
Objective As the cost-effectiveness evaluation of cinacalcet and conventional therapy in China has not been reported, the objective of this study was to make a pharmacoeconomic evaluation of cinacalcet specific to the Chinese healthcare setting in ...
Bin Wu, Lin Liu, Xiaoyang Lu, Dongsheng Hong, Kuifen Ma   +4 more
doaj   +1 more source

Anti-parathyroid treatment effectiveness and persistence in incident haemodialysis patients with secondary hyperparathyroidism

Nefrología (English Edition), 2016
Background: Anti-parathyroid treatment initiation and discontinuation are important decisions in chronic haemodialysis (HD) patients, where pill burden is often excessive.
Angel Luis Martín de Francisco, Iain Andrew Gillespie, Ioanna Gioni, Jürgen Floege, Florian Kronenberg, Daniele Marcelli, David Collins. Wheeler, Marc Froissart, Tilman Bernhard. Drueke   +8 more
doaj   +3 more sources