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Pathogenesis of secondary hyperparathyroidism [PDF]
Secondary hyperparathyroidism is a universal complication in patients with chronic renal failure. Hyperplasia of the parathyroid glands is typically seen in these patients. In early renal failure, alteration in vitamin metabolism, decreased levels of calcitriol and moderate decreases in ionized calcium may allow greater synthesis and secretion of PTH ...
Slatopolsky, Eduardo +2 more
openaire +4 more sources
PARATHYROID CANCER OCCURRING IN RELAPSING SECONDARY HYPERPARATHYROIDISM
We present a clinical case of parathyroid cancer in a patient with relapsing secondary hyperparathyroidism at 4 years after subtotal parathyroidectomy.
I. V. Kotova +2 more
doaj +2 more sources
Secondary and tertiary hyperparathyroidism in chronic kidney disease [PDF]
In the treatment of secondary hyperparathyroidism of end-stage chronic kidney disease, vitamin D receptor activation and allosteric modulators of the calcium-sensing receptor inhibit glandular hyperplasia, reduce parathyroid hormone levels, impact on ...
Lilit V. Egshatyan +2 more
doaj +2 more sources
Secondary hyperparathyroidism: recurrence after total parathyroidectomy with autotransplantation
BACKGROUND Secondary hyperparathyroidism is common in patients with end-stage chronic kidney disease. If drug therapy fails, total parathyroidectomy with autotransplantation of parathyroid tissue into the forearm (PTX-AT) is the most widely ...
Lukas Steffen +3 more
doaj +2 more sources
Prevalence of Secondary Hyperparathyroidism in Hemo- Dialysis Patients
Introduction: One persistent complication of chronic kidney disease is secondary hyperparathyroidism. Early diagnosis of this disease will reduce morbidity in patients undergoing hemodialysis.
Awais Amjad +4 more
doaj +2 more sources
DIAGNOSTICS AND TREATMENT OF PRIMARY AND SECONDARY HYPERPARATHYROIDISM
The experience of treatment of 41 patients (aged 32–67years) was presented in the article. The duration of disease was 2–5 years. Primary hyperparathyroidism was diagnosed in 16 patients and secondary — in 25. Diagnostics of the disease included clinical
M. F. Zarivchatskiy +4 more
doaj +2 more sources
Mechanism of calcitriol regulating parathyroid cells in secondary hyperparathyroidism
A common consequence of chronic renal disease is secondary hyperparathyroidism (SHPT) and is closely related to the mortality and morbidity of uremia patients.
Zeli Xiang +4 more
doaj +1 more source
Hypercalciuria and hyperparathyroidism — is there always a connection?
Hypercalciuria is a pathological condition characterized by an excess of daily calcium excretion. A high concentration of urine calcium can initiate stone formation. There are several types of hypercalciuria, each requires an individual approach.
S. S. Mirnaya, A. K. Eremkina
doaj +1 more source
Pathogenesis of secondary hyperparathyroidism [PDF]
The past 20 years has witnessed a dramatic improvement in our understanding of the factors involved in the pathogenesis of secondary hyperparathyroidism in chronic renal insufficiency. The major causes are retention of phosphorus, relatively low levels of serum calcium, and decreased 1,25-(OH)2D3 (calcitriol) levels.
E, Slatopolsky, J A, Delmez
openaire +4 more sources
Pathogenesis of Secondary Hyperparathyroidism [PDF]
Chronic renal failure is the primary cause of secondary hyperparathyroidism (SHPT). Patients with mineral metabolism disorders commonly present with low serum calcium levels, hyperphosphatemia, and calcitriol deficiency. In normal renal function subjects, parathyroid cells have a low turnover and rarely undergo mitoses.
M.G. Cozzolino +5 more
openaire +3 more sources

