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Mechanism of calcitriol regulating parathyroid cells in secondary hyperparathyroidism
A common consequence of chronic renal disease is secondary hyperparathyroidism (SHPT) and is closely related to the mortality and morbidity of uremia patients.
Zeli Xiang +4 more
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Hypercalciuria and hyperparathyroidism — is there always a connection?
Hypercalciuria is a pathological condition characterized by an excess of daily calcium excretion. A high concentration of urine calcium can initiate stone formation. There are several types of hypercalciuria, each requires an individual approach.
S. S. Mirnaya, A. K. Eremkina
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Pathogenesis of secondary hyperparathyroidism [PDF]
The past 20 years has witnessed a dramatic improvement in our understanding of the factors involved in the pathogenesis of secondary hyperparathyroidism in chronic renal insufficiency. The major causes are retention of phosphorus, relatively low levels of serum calcium, and decreased 1,25-(OH)2D3 (calcitriol) levels.
E, Slatopolsky, J A, Delmez
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Pathogenesis of Secondary Hyperparathyroidism [PDF]
Chronic renal failure is the primary cause of secondary hyperparathyroidism (SHPT). Patients with mineral metabolism disorders commonly present with low serum calcium levels, hyperphosphatemia, and calcitriol deficiency. In normal renal function subjects, parathyroid cells have a low turnover and rarely undergo mitoses.
M.G. Cozzolino +5 more
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Objective: To determine clinical decision limits (cut off points) for vitamin D deficiency based on secondary hyperparathyroidism. Study Design: Cross sectional study.
Afshan Bibi +5 more
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Secondary Hyperparathyroidism in Osteomalacia [PDF]
Twenty-one patients with histologically proved osteomalacia from various causes were investigated for biochemical and radiological evidence of osteomalacia and secondary hyperparathyroidism. Among the 15 who maintained a normal serum calcium, seven had a raised phosphate excretion index, seven had a raised serum alkaline phosphatase, and six had ...
N C, Thalassinos, S, Wicht, G F, Joplin
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Disputable Issues of Etiology and Pathogenesis of Tertiary Hyperparathyroidism
Hyperparathyroidism is a clinical and laboratory syndrome characterized by high production of the chief cells of the parathyroid hormone, a calcium-phosphorus metabolism disorder and the organ failure (kidneys, bone tissue).There are primary, secondary ...
G. A. Bersenev +2 more
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Secondary hyperparathyroidism is a complex pathology that develops as chronic kidney disease progresses. The retention of phosphorus and the reductions in calcium and vitamin D levels stimulate the synthesis and secretion of parathyroid hormone as well ...
María E. Rodríguez-Ortiz +1 more
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Brown Tumor of the Cervical Spines: A Case Report with Literature Review [PDF]
To report a rare case of axis brown tumor and to review literature of cervical spine brown tumor. Brown tumor is a rare bone lesion, incidence less than 5% in primary hyperparathyroidism.
Mohammad Dursi Alfawareh +3 more
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Surgical Management of Secondary Hyperparathyroidism
Secondary hyperparathyroidism (SHPT) affects a majority of patients with chronic kidney disease (CKD) of stage 3 or worse. Despite the development of calcimimetics and their effectiveness in treating SHPT, many patients continue to fail medical ...
Gabrielle K. Steinl, Jennifer H. Kuo
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