Results 11 to 20 of about 29,158 (227)
Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism. [PDF]
Ther Apher DialABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Koiwa F, Honda D, Akari S, Akizawa T.
europepmc +2 more sources
Pathogenesis of secondary hyperparathyroidism [PDF]
Nephrology Dialysis Transplantation, 1994 The past 20 years has witnessed a dramatic improvement in our understanding of the factors involved in the pathogenesis of secondary hyperparathyroidism in chronic renal insufficiency. The major causes are retention of phosphorus, relatively low levels of serum calcium, and decreased 1,25-(OH)2D3 (calcitriol) levels.
E, Slatopolsky, J A, Delmez
openaire +4 more sources
Pathogenesis of Secondary Hyperparathyroidism [PDF]
The International Journal of Artificial Organs, 2009 Chronic renal failure is the primary cause of secondary hyperparathyroidism (SHPT). Patients with mineral metabolism disorders commonly present with low serum calcium levels, hyperphosphatemia, and calcitriol deficiency. In normal renal function subjects, parathyroid cells have a low turnover and rarely undergo mitoses.
M.G. Cozzolino +5 more
openaire +3 more sources
European multicentre study on outcome of surgery for sporadic primary hyperparathyroidism
BJS (British Journal of Surgery), EarlyView., 2020 Some 5861 patients undergoing first‐time surgery for sporadic primary hyperparathyroidism were registered in the Eurocrine® database between 2015 and 2018. The use of intraoperative parathyroid hormone measurement decreased the risk of conversion and persistent hypercalcaemia.
A. Bergenfelz +3 more
wiley +1 more source
BJS (British Journal of Surgery), EarlyView., 2020 This study investigated postoperative complications after surgery for medullary thyroid carcinoma (MTC) in Europe. Hypoparathyroidism, recurrent laryngeal nerve palsy and bleeding requiring reoperation occurred in 170 (26·2 per cent), 62 (13·7 per cent) and 17 (2·6 per cent) patients respectively.
D.‐J. van Beek +18 more
wiley +1 more source
Brown Tumor of the Cervical Spines: A Case Report with Literature Review [PDF]
Asian Spine Journal, 2015 To report a rare case of axis brown tumor and to review literature of cervical spine brown tumor. Brown tumor is a rare bone lesion, incidence less than 5% in primary hyperparathyroidism.
Mohammad Dursi Alfawareh +3 more
doaj +1 more source
Surgical Management of Secondary Hyperparathyroidism
Kidney International Reports, 2021 Secondary hyperparathyroidism (SHPT) affects a majority of patients with chronic kidney disease (CKD) of stage 3 or worse. Despite the development of calcimimetics and their effectiveness in treating SHPT, many patients continue to fail medical ...
Gabrielle K. Steinl, Jennifer H. Kuo
doaj +1 more source
Localization Strategy Prior to Radiofrequency Ablation for Primary and Secondary Hyperparathyroidism
Biomedicines, 2023 Objective: Preoperative localization in patients with primary or secondary hyperparathyroidism before radiofrequency ablation (RFA) is crucial. There is currently a lack of consensus regarding imaging protocol.
Chih-Ying Lee +9 more
doaj +1 more source
F1000Research, 2020 Secondary hyperparathyroidism is a complex pathology that develops as chronic kidney disease progresses. The retention of phosphorus and the reductions in calcium and vitamin D levels stimulate the synthesis and secretion of parathyroid hormone as well ...
María E. Rodríguez-Ortiz +1 more
doaj +1 more source
Advances in Oral and Maxillofacial Surgery, 2021 Introduction: The brown tumour is a benign lesion resulting from an anomaly of bone metabolism in the context of primary or secondary hyperparathyroidism.
Ulrich Opoko +5 more
doaj +1 more source