A highly contiguous, scaffold-level nuclear genome assembly for the fever tree (Cinchona pubescens Vahl) as a novel resource for Rubiaceae research [PDF]
The Andean fever tree (Cinchona L.; Rubiaceae) is a source of bioactive quinine alkaloids used to treat malaria. C. pubescens Vahl is a valuable cash crop within its native range in northwestern South America, however, genomic resources are ...
Nataly Allasi Canales +11 more
doaj +8 more sources
The complete chloroplast genome of the national tree of Peru, quina (Cinchona officinalis L., Rubiaceae) [PDF]
Here, we report the first complete chloroplast (cp) genome of Cinchona officinalis. This cp genome has a 156,984 bp in length with typical quadripartite structure, containing a large single copy (LSC) region (83,929 bp) and an 18,051 bp small single-copy
Carlos I. Arbizu +5 more
doaj +4 more sources
Synthesis, Antibacterial Properties and Molecular Docking Studies of Nitrogen Substituted 9-(((4X-But-2-ynyloxy)methyl)-1,2,3-triazolyl)–Cinchona Alkaloid Conjugates [PDF]
The year 2024 marked the 80th anniversary of Woodward’s total synthesis of quinine. Quinine is a natural alkaloid from the bark of the cinchona tree that has been used for years as an antimalarial drug.
Gulim K. Mukusheva +12 more
doaj +3 more sources
Smallholder farmers’ knowledge on management of Cinchona in the Democratic Republic of the Congo [PDF]
Background and aims – Cinchona (Rubiaceae) tree bark is the key source of quinine alkaloids used as malaria treatment. Cinchona trees were introduced to Democratic Republic of the Congo (DRC) in the early 20th century. Currently, the eastern DRC accounts
Bezawit Mekonnen +10 more
doaj +4 more sources
The Cinderella tree, <i>Quillaja saponaria</i> - A soap story. [PDF]
Our current understanding of plants has been shaped by the entwining of different cultures. The Chilean soapbark tree, traditionally valued as a source of natural soap, was shown by serendipitous research in France in the 1900s to produce compounds that can boost the immune response to vaccines.
Osbourn A.
europepmc +2 more sources
Genetic characterization of fragmented populations of Cinchona officinalis L. (Rubiaceae), a threatened tree of the northern Andean cloud forests [PDF]
AbstractCinchona officinalisL., a tree species endemic to the cloud forests of the northern Tropical Andes, has suffered from historical bark harvesting for extraction of antimalarial compounds and has also experienced recent demographic losses from high rates of deforestation.
Augusta Cueva-Agila +5 more
openaire +2 more sources
Efforts to optimize ex vitro transfer techniques of un-rooted in vitro shoots of Cinchona spp. (Rubiaceae) a native tree of the andean forests, are crucial for promoting sustainable cultivation practices of this medicinal plant.
Juan David Saavedra Correa +2 more
doaj +2 more sources
AbstractBackgroundThe Andean Fever tree (Cinchona L.; Rubiaceae) is the iconic source of bioactive quinine alkaloids, which have been vital to treating malaria for centuries. C. pubescens Vahl, in particular, has been an essential source of income for several countries within its native range in north-western South America.
Nataly Allasi Canales +11 more
openaire +2 more sources
The Spread of Non-native Plant Species Collection of Cibodas Botanical Garden into Mt. Gede Pangrango National Park [PDF]
The role of botanic garden in spread of non-native plant species has concerned of international worldwide. This study aimed to study the extent of non-native plant species from Cibodas Botanical Garden (CBG) which invades into natural rainforest.
Musyarofah Zuhri, Zaenal Mutaqien
doaj +2 more sources
Galápagos Rail Laterallus spilonotus population change associated with habitat invasion by the Red-barked Quinine Tree Cinchona pubescens [PDF]
SummarySpecies on oceanic islands are more likely to be endemic as well as more extinction-prone than those on continents. The Galápagos Rail Laterallus spilonotus, endemic to the Galápagos Archipelago, is presently known to occur on just four of its seven previously occupied islands and is facing multiple threats to its persistence.
W. GREGORY SHRIVER +4 more
openaire +2 more sources

