Results 41 to 50 of about 26,742 (266)

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin   +8 more
wiley   +1 more source

Determining factors of university students' binge-watching attitudes

open access: yesHeliyon
Binge-watching (BW), defined as watching multiple episodes of a series or program in a single sitting, is recognized as a new and widespread form of viewing, especially with online streaming services.
Murat Aytas, Ismail Berkay Topatan
doaj   +1 more source

Ana Hedberg Olenina: Psychomotor Aesthetics: Movement and Affect in Modern Literature and Film

open access: yesApparatus. Film, Media and Digital Cultures of Central and Eastern Europe, 2020
Review of Ana Hedberg Olenina's Psychomotor Aesthetics: Movement and Affect in Modern Literature and Film (2020).
Amanda Jane Barbour
doaj   +1 more source

INTERNATIONAL FORUM “OLD AND NEW MEDIA: ALONG THE PATH TOWARDS A NEW AESTHETICS” / МЕЖДУНАРОДНЫЙ ФОРУМ «СТАРЫЕ И НОВЫЕ МЕДИА: ПУТИ К НОВОЙ ЭСТЕТИКЕ» [PDF]

open access: yesНаука телевидения, 2019
The article analyzes the results of the International Forum “Starye i novye media: put k novoy estetike:” [“Old and New Forms of Media: Paths Towards New Aesthetics”], which took place in Moscow on March 26–29, 2019.
BOGATYRYOVA ELENA A.
doaj   +1 more source

Effects of Causal Beliefs About Gout on Public Views About Gout Management: A Randomized Experimental Study

open access: yesArthritis Care &Research, EarlyView.
Objective Despite well‐described biologic causes, the public views unhealthy lifestyle choices as the primary cause of gout. This study investigated how causal beliefs about gout influence the public's views about its management. Methods In a randomized study, 201 members of the public viewed one of two 2‐minute videos about gout.
Rachel Murdoch   +6 more
wiley   +1 more source

Artificial intelligence and the transformation of journalism: A systematic review of opportunities, challenges, and ethical implications [PDF]

open access: yesCyberspace Studies
ackground: Over the past decade, advances in machine learning, natural language processing, and generative artificial intelligence have enabled news organizations to automate routine reporting tasks, enhance investigative capabilities, and deliver ...
Babak Dariush, Faezeh Piriyaei
doaj   +1 more source

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights From a Large International Sicca Registry

open access: yesArthritis Care &Research, EarlyView.
Objective The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögren's International Collaborative Clinical Alliance (SICCA) cohort. Methods We performed a retrospective analysis examining 16 ocular symptoms (most graded 0–4) and artificial tear (AT) use (graded 0–3) as predictors of DED signs (abnormal ocular ...
Pragnya R. Donthineni   +7 more
wiley   +1 more source

Novos caminhos do teatro de sombras: performance e work in progress

open access: yesMóin-Móin, 2018
Este artigo apresenta os caminhos da pesquisa com teatro de sombra da Cia Quase Cinema dando especial ênfase aos processos criativos e questões conceituais que ajudam a pensar onde o teatro de sombras contemporâneo se encontra com as artes plásticas ...
Ronaldo Robles, Silvia Godoy
doaj  

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