Results 101 to 110 of about 205,504 (355)
MRI Epicenters Differentiate Spatiotemporal Patterns of Neurodegeneration in Parkinson's Disease
Advanced Science, EarlyView.A connectivity‐based MRI epicenter model identifies two Parkinson's disease subtypes: subtype 1 with infratentorial‐dominant epicenters, severe motor symptoms, and rapid progression; and subtype 2 with supratentorial‐dominant epicenters with mild progression.
Xiaojie Duanmu +23 more
wiley +1 more source
Cingulate cortex function and multi-modal connectivity mapped using intracranial stimulation
NeuroImage, 2020 The cingulate cortex is part of the limbic system. Its function and connectivity are organized in a rostro-caudal and ventral-dorsal manner which was addressed by various other studies using rather coarse cortical parcellations.
Irina Oane +10 more
doaj +1 more source
Neural signatures of cognitive flexibility and reward sensitivity following nicotinic receptor stimulation in dependent smokers : a randomized trial [PDF]
, 2017 IMPORTANCE Withdrawal from nicotine is an important contributor to smoking relapse. Understanding how reward-based decision making is affected by abstinence and by pharmacotherapies such as nicotine replacement therapy and varenicline tartrate may aid ...
Aronson, Sarah E. +5 more
core +2 more sources
SpaBalance: Balanced Learning for Efficient Spatial Multi‐Omics Decoding
Advanced Science, EarlyView.SpaBalance is a computational framework that harmonizes multi‐omics learning via gradient equilibrium and dual‐stream feature decomposition, achieving superior clustering accuracy, biological interpretability, and scalable integration of three or more spatial omics modalities.
Yingbo Cui +8 more
wiley +1 more source
Activity in human reward-sensitive brain areas is strongly context dependent [PDF]
, 2005 Functional neuroimaging research in humans has identified a number of brain areas that are activated by the delivery of primary and secondary reinforcers.
Sander Nieuwenhuis +39 more
core +4 more sources
Advanced Intelligent Systems, EarlyView.This study, utilizing two large‐cohort datasets, employs interpretable neural networks. It demonstrates that incorporating brain morphology and functional and structural networks enhances predictive accuracy for general psychopathology and its dimensions.
Jing Xia, Nanguang Chen, Anqi Qiu
wiley +1 more source
Blood α‐Synuclein Separates Parkinson's Disease from Dementia with Lewy Bodies
Annals of Neurology, EarlyView.Objective Aggregation of misfolded α‐synuclein (aSyn) within the brain is the pathologic hallmark of Lewy body diseases (LBDs), including Parkinson's disease (PD), and dementia with Lewy bodies (DLB) disease. Although evidence exists for aSyn “strains,” conformations with distinct biological properties, biomarkers for PD versus DLB are lacking.
George T. Kannarkat +17 more
wiley +1 more source
A neuroimaging study of pleasant and unpleasant olfactory perceptions of virgin olive oil [PDF]
, 2016 Functional magnetic resonance imaging (fMRI) has been used to collect information from neurons that receive direct input from olfactory bulbs when subjects smell virgin olive oil. The pleasant aroma of three extra virgin olive oils (var.
Aparicio López, Ramón +4 more
core +3 more sources
Annals of Neurology, EarlyView.Objectives Prospective studies demonstrated that essential tremor is a risk factor for Parkinson's disease. Identifying clinical markers for conversion from essential tremor to essential tremor‐Parkinson's disease would be of considerable value. Rest tremor can be present in advanced essential tremor and may be a harbinger of conversion. We examined (1)
Elan D. Louis +3 more
wiley +1 more source
Interactions between visceral afferent signaling and stimulus processing [PDF]
, 2015 Visceral afferent signals to the brain influence thoughts, feelings and behaviour. Here we highlight the findings of a set of empirical investigations in humans concerning body-mind interaction that focus on how feedback from states of autonomic arousal ...
Anderson +62 more
core +2 more sources