The neural correlates of desire. [PDF]
In an event-related fMRI study, we scanned eighteen normal human subjects while they viewed three categories of pictures (events, objects and persons) which they classified according to desirability (desirable, indifferent or undesirable).
Hideaki Kawabata, Semir Zeki
doaj +1 more source
Die Rolle der Zielnähe und der investierten Anstrengung für den erwarteten Wert einer Handlung [PDF]
In human neuroscientific research, there has been an increasing interest in how the brain computes the value of an anticipated outcome. However, evidence is still missing about which valuation related brain regions are modulated by the proximity to an ...
Schmitt, Ruth
core
Sub-cortical and brainstem sites associated with chemo-stimulated increases in ventilation in humans [PDF]
We investigated the neural basis for spontaneous chemo-stimulated increases in ventilation in awake, healthy humans. Blood oxygen level dependent (BOLD) functional MRI was performed in nine healthy subjects using T2weighted echo planar imaging.
Ackland +67 more
core +2 more sources
A Replicable and Generalizable Neuroimaging‐Based Indicator of Pain Sensitivity Across Individuals
Humans differ in their sensitivity to pain. With six large and diverse fMRI datasets (total N = 1046), this study finds that such individual differences in pain sensitivity can be tracked by fMRI responses to painful stimuli. A highly generalizable machine learning model is further built to predict pain sensitivity across all datasets and analgesic ...
Li‐Bo Zhang +7 more
wiley +1 more source
Resting state electrical brain activity and connectivity in fibromyalgia. [PDF]
The exact mechanism underlying fibromyalgia is unknown, but increased facilitatory modulation and/or dysfunctional descending inhibitory pathway activity are posited as possible mechanisms contributing to sensitization of the central nervous system.
Sven Vanneste +3 more
doaj +1 more source
State-dependent changes of connectivity patterns and functional brain network topology in Autism Spectrum Disorder [PDF]
Anatomical and functional brain studies have converged to the hypothesis that Autism Spectrum Disorders (ASD) are associated with atypical connectivity.
Barttfeld, Pablo +6 more
core +2 more sources
GABA quantification in human anterior cingulate cortex
Abstractγ-Aminobutyric acid (GABA) is a primary inhibitory neurotransmitter in the human brain. It has been shown that altered GABA concentration plays an important role in a variety of psychiatric and neurological disorders. The main purpose of this study was to propose a combination of PRESS and MEGA-PRESS acquisitions for absolute GABA ...
Jan Weis +5 more
openaire +7 more sources
Mesenchymal stromal cells (MSC) are considered a promising alternative for neuropathic pain (NP) treatment, but underlying mechanisms remain elusive. Huang et al. illustrate that a Npy2r sensory neuron‐related lung–brain axis contributes to MSC analgesia.
Jing Huang +25 more
wiley +1 more source
The role of the left head of caudate in suppressing irrelevant words [PDF]
Suppressing irrelevant words is essential to successful speech production and is expected to involve general control mechanisms that reduce interference from task-unrelated processing.
Ali, N. +4 more
core +1 more source
Dynamic Neural Deactivation Bridges Direct and Competitive Inhibition Processes
Dynamic neural deactivation bridges traditionally distinct inhibitory mechanisms—direct inhibition and competition‐induced inhibition—revealing a common neural signature across modalities. Multimodal neuroimaging and behavioral experiments demonstrate a temporal dynamic characterized by progressive frontoparietal activation decay and enhanced sensory ...
Zhenhong He +6 more
wiley +1 more source

