Results 81 to 90 of about 18,245 (244)

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Cinnamaldehyde-Based Poly(ester-thioacetal) To Generate Reactive Oxygen Species for Fabricating Reactive Oxygen Species-Responsive Nanoparticles

, 2018
Due to the high oxidative stress of the tumor microenvironment, more and more researchers have been devoted to reactive oxygen species (ROS)-responsive nanodrug delivery systems for anticancer therapy.
Wenxia Gao (1515058), Yuji Pu (2281027), Long Xu, Zhaoyuan Guo, Hai Zhang, Xuequan Zhang, Jianfeng Zhang, Jun Cao, Hai Zhang (41608), Jianfeng Zhang (219107), Bin He (75597), Mingying Zhao (5433830), Zhaoyuan Guo (5982428), Xuequan Zhang (703572), Bin He, Wenxia Gao, Jun Cao (32440), Mingying Zhao, Long Xu (218743), Yuji Pu   +19 more
core   +1 more source

Antibacterial film with chitosan-cinnamaldehyde Schiff base: Fabrication and application in chilled mutton preservation

Future Foods
Release in response to stimuli such as enzyme, pH, temperature, and light effectively reduces the loss of volatile active compounds and controls the release of active ingredients.
Lei Wen, Pengfei Du, Weiting Wang, Yaobo Liu, Peng Hu, Jianfang Cao, Yanli Ma   +6 more
doaj   +1 more source

Neohesperidin Alleviates Ferroptosis in Doxorubicin‐Induced Cardiotoxicity via Mettl3‐m6A‐Nrf2 Signaling

Phytotherapy Research, EarlyView.
Neohesperidin alleviates doxorubicin‐induced cardiotoxicity by inhibiting METTL3‐mediated m6A modification of Nrf2 mRNA, thereby regulating Nrf2 and suppressing ferroptosis. ABSTRACT Doxorubicin (DOX) has antitumor efficacy, but its clinical application is restricted by multiple side effects, especially cardiotoxicity.
Ruijia Wen, Xin Dong, Haowen Zhuang, Yusheng Huang, Mengyuan Wang, Zhongzheng Zhang, Jinhong Chen, Wei Wang, Chun Li, Junyan Wang   +9 more
wiley   +1 more source

University teaching of mass spectrometry as a key practical technique within the context of a fully integrated, spiral curriculum

Rapid Communications in Mass Spectrometry, EarlyView.
Rationale Mass spectrometry (MS) is introduced to high school students in the UK in many pre‐university course syllabi. As such, we have identified the use of MS as a key technique that should be taught practically to undergraduates from the outset of their studies.
Andrew F. Worrall, Craig D. Campbell, Megan O. Midson, Malcolm I. Stewart   +3 more
wiley   +1 more source

Advances in Unconventional and Sustainable Synthetic Approaches to Benzopyran Scaffolds

The Chemical Record, EarlyView.
This review provides a comprehensive and critical analysis of low‐impact synthetic methodologies reported in the last 8 years (2018–2026) for the construction of benzopyran‐derived scaffolds, such as coumarins, flavones, chromones, chromenes, and chromanes. The benzopyran scaffold is a versatile family of heterocycles found in a wide range of bioactive
Nathalia B. Sá, Patrick C. Nobre, Isabelly O. Ferreira, Juliano B. Azeredo, Vanessa Nascimento   +4 more
wiley   +1 more source

Bioactivities of HP-β-CD/cinnamaldehyde complex

, 2012
[[abstract]]Cinnamaldehyde has been used frequently in medical treatment, some researches indicated that Cinnamaldehyde can use as antimicrobial and antifungal. There are two main goals in our study.
Wu, Chanying
core  

Immune suppressive effect of cinnamaldehyde due to inhibition of proliferation and induction of apoptosis in immune cells: implications in cancer.

PLoS ONE, 2014
BackgroundBesides its anti-inflammatory effects, cinnamaldehyde has been reported to have anti-carcinogenic activity. Here, we investigated its impact on immune cells.MethodsActivation of nuclear factor-κB by cinnamaldehyde (0-10 µg/ml) alone or in ...
Franziska Roth-Walter, Anna Moskovskich, Cristina Gomez-Casado, Araceli Diaz-Perales, Kumiko Oida, Josef Singer, Tamar Kinaciyan, Heidemarie C Fuchs, Erika Jensen-Jarolim   +8 more
doaj   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

Parthenogenetic Haemaphysalis longicornis acetylcholinesterases are triggered by the repellent effect of cinnamaldehyde, a primary compound found in cinnamon oil

Ticks and Tick-Borne Diseases
The control and prevention of ticks and tick-borne diseases rely on chemical insecticides and repellents. Plant-derived compounds potentially represent new and safer repellents.
Ceyan kuang, Jie Cao, Yongzhi Zhou, Houshuang Zhang, Yanan Wang, Jinlin Zhou   +5 more
doaj   +1 more source