Results 91 to 100 of about 18,245 (244)

Untargetted Metabolomic Exploration of the Mycobacterium tuberculosis Stress Response to Cinnamon Essential Oil

Biomolecules, 2020
The antimycobacterial activity of cinnamaldehyde has already been proven for laboratory strains and for clinical isolates. What is more, cinnamaldehyde was shown to threaten the mycobacterial plasma membrane integrity and to activate the stress response ...
Elwira Sieniawska, Rafał Sawicki, Joanna Golus, Milen I. Georgiev   +3 more
doaj   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Selectivity control in Pt-catalyzed cinnamaldehyde hydrogenation [PDF]

, 2015
Chemoselectivity is a cornerstone of catalysis, permitting the targeted modification of specific functional groups within complex starting materials. Here we elucidate key structural and electronic factors controlling the liquid phase hydrogenation of ...
Durndell, Lee J., Lee, Adam F., Parlett, Christopher M A; id_orcid, Parlett, Christopher M.A., Durndell, LJ, Isaacs, Mark A., Hondow, NS, Lee, AF, Isaacs, MA, Durndell, Lee, Wilson, K, Issacs, Mark A., Hondow, Nicole S., Lee, Adam, Parlett, CMA, Wilson, Karen   +15 more
core   +1 more source

Improvement of cinnamaldehyde addition on properties of whey protein concentrate gel

, 2021
The nano-emulsions and microcapsules were used to improve the hydrophilicity of cinnamaldehyde, which were then added to whey protein concentrate solution. Protein gel was produced by heat-induced method. The rheological property, water holding capacity,
Bin, LI, Yan, LI, Huan-huan, CUI, Feng-da, QIN   +3 more
core   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Cinnamaldehyde and Curcumin Prime Akt2 for Insulin-Stimulated Activation

, 2022
In this study, the effects of cinnamaldehyde and curcumin on Akt2, a serine/threonine protein kinase central to the insulin signaling pathway, were examined in preadipocytes. Cinnamaldehyde or curcumin treatment increased Akt2 phosphorylation at multiple
Le, Thuc T., Yasuyo Urasaki, Urasaki, Yasuyo, Thuc T. Le   +3 more
core   +1 more source

Advances in organic UV filters for sunscreens over the past decade

Photochemistry and Photobiology, EarlyView.
Highlighted organic UV filter frameworks that have been described for sunscreens over the past decade divided into three groups: derivatives of or inspired by approved organic UV filters, natural product‐based compounds, and miscellaneous. Abstract Ultraviolet (UV) radiation is a major environmental factor in photoaging, erythema, and skin cancer ...
Gabriela Zanella Marcon, Maria Carolina Theisen, Andressa Motta Castro, Giovana Jones Radke, Fernando Fumagalli   +4 more
wiley   +1 more source

Engineered surface strategies to manage dental implant‐related infections

Periodontology 2000, EarlyView.
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza, Bruna E. Nagay, Rodrigo Martins, Martinna Bertolini, Jamil A. Shibli, Conrado Aparicio, Magda Feres, Valentim A. R. Barão   +7 more
wiley   +1 more source

Emerging locally delivered antimicrobial and immunomodulatory approaches for the prevention/treatment of peri‐implant diseases

Periodontology 2000, EarlyView.
Abstract Peri‐implant diseases are dysbiosis‐mediated inflammatory disorders that occur in susceptible hosts. Antimicrobials and immunomodulatory agents therefore might be pertinent as adjunctive measures in the treatment of such disorders. The aim of this narrative review was to examine the existing evidence and assess the effectiveness of emerging ...
Alberto Monje, Ettore Amerio, Irene Mallor, Conrado Aparicio   +3 more
wiley   +1 more source

Potency of cinnamaldehyde of cinnamon oil as an antidiabetic compound [PDF]

, 2011
Cafeic  and  cinnamic  compounds  have  been  reported  to give  an  excellent performance  as  α-glucosidase  inhibitor. Inhibition  of  α-glucosidase  in  the intestine of mammals are able to lower blood sugar  levels of the carbohydrates metabolism ...
Prasetya, Nor Basid A.; Laboratory of Analysis of Chemistry, Mayors of Chemistry, faculty of Mathematics and Natural Science, Diponegoro University, ., Ismiyarto; Laboratory of Organic Chemistry, Mayors of Chemistry, faculty of Mathematics and Natural Science, Diponegoro University, S., Purbowatiningrum R.; Laboratory of Biochemistry, Mayors of Chemistry, faculty of Mathematics and Natural Science, Diponegoro University, ., Ngadiwiyana; Laboratory of Organic Chemistry, Mayors of Chemistry, faculty of Mathematics and Natural Science, Diponegoro University   +3 more
core   +1 more source