Results 91 to 100 of about 70,841 (213)

Fraternal cooperation of hierarchical cancer parallels metazoan multicellularity and eusociality

Biological Reviews, Volume 101, Issue 1, Page 400-418, February 2026.
ABSTRACT Metazoan multicellularity and eusociality — both outcomes of the fraternal major transitions — have numerous features in common such as uneven distribution of group‐establishing potential. In addition to this framework, I argue herein that the group‐forming principles of metazoan multicellularity and eusociality are analogous to hierarchical ...
Jibeom Choi
wiley   +1 more source

Rational design and whole-genome predictions of single guide RNAs for efficient CRISPR/Cas9-mediated genome editing in Ciona [PDF]

, 2016
The CRISPR/Cas9 system has emerged as an important tool for a wide variety of genome engineering applications, including reverse genetic screens. Previously, we described the implementation of the CRISPR/Cas9 system to induce tissue-specific mutations at
Christiaen, Lionel, Gandhi, Shashank, Stolfi, Alberto   +2 more
core  

Recombinant Proteins: A Molecular Tool to Understand Marine Adhesion and to Advance Biomaterials

Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
The production of recombinant proteins represents a fundamental step in the characterisation of marine invertebrate adhesives and in the development of bio‐inspired glues. The association of these proteins with other components such as ions, proteins, polysaccharides, or polymers enables the fabrication of biomaterials for various healthcare ...
Alessandra Whaite, Emilie Duthoo, Mathilde Lefevre, Elise Hennebert, Patrick Flammang   +4 more
wiley   +1 more source

Multi‐Omics‐Driven Adaptive Management of Biological Invasions: Toward a Proactive, Predictive, and Integrative Framework

Biological Diversity, Volume 2, Issue 4, Page 163-192, December 2025.
A proactive, predictive, and integrative framework that integrates multi‐omics innovations with ecological modeling and big data analytics to guide adaptive interventions and governance in invasive species management. By integrating multi‐omics insights with advanced ecological modeling, remote sensing, artificial intelligence, and cross‐disciplinary ...
Aibin Zhan
wiley   +1 more source

Characterization of DNA methylation as a function of biological complexity via dinucleotide inter-distances

, 2015
We perform a statistical study of the distances between successive occurrencies of a given dinucleotide in the DNA sequence for a number of organisms of different complexity.
Castellani, Gastone C., Cristadoro, Giampaolo, Esposti, Mirko Degli, Lenci, Marco, Monti, Barbara, Paci, Giulia, Remondini, Daniel   +6 more
core   +1 more source

THE PHOTIC SENSITIVITY OF CIONA INTESTINALIS [PDF]

Journal of General Physiology, 1918
1. Ciona possesses two means of responding to an increase in the intensity of illumination. One is by means of a local reaction; the other is by a retraction reflex of the body as a whole. 2. The "ocelli" are not photoreceptors. The photosensitive area is in the intersiphonal region containing the neural mass.
openaire   +2 more sources

Divergent mechanisms regulate conserved cardiopharyngeal development and gene expression in distantly related ascidians

eLife, 2014
Ascidians present a striking dichotomy between conserved phenotypes and divergent genomes: embryonic cell lineages and gene expression patterns are conserved between distantly related species. Much research has focused on Ciona or Halocynthia spp.
Alberto Stolfi, Elijah K Lowe, Claudia Racioppi, Filomena Ristoratore, C Titus Brown, Billie J Swalla, Lionel Christiaen   +6 more
doaj   +1 more source

Why Homoscleromorph Sponges Have Ciliated Epithelia: Evidence for an Ancestral Role in Mucociliary Driven Particle Flux

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 344, Issue 8, Page 505-516, December 2025.
Epithelia are typically ciliated, except in sponges. Of all Porifera only Homoscleromorphs have motile cilia on their epithelia. Our data highlight the presence of cilia and mucociliary particle transport as a common feature of metazoa and a secondary loss in other sponge lineages.
Veronica L. Price, Anudi Nanayakkara, Andrea Pasini, Elsa Bazellières, Amelie Vernale, Caroline Rocher, Carole Borchiellini, Andre Le Bivic, Emmanuelle Renard, Sally P. Leys   +9 more
wiley   +1 more source

Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology [PDF]

, 2016
Plants and many lower organisms, but not mammals, express alternative oxidases (AOXs) that branch the mitochondrial respiratory chain, transferring electrons directly from ubiquinol to oxygen without proton pumping.
Braun, Thomas, de Angelis, Martin Hrabe, Dhandapani, Praveen K., Dufour, Eric, Fuchs, Helmut, Gailus-Durner, Valerie, Gainutdinov, Timur, Gellerich, Frank N., German Mouse Clinic Consortium, Gizatullina, Zemfira, Heidler, Juliana, Holmstrom, Kira M., Jacobs, Howard T., Nandania, Jatin, Rustin, Pierre, Salwig, Isabelle, Szibor, Marten, Velagapudi, Vidya, Wietelmann, Astrid, Wittig, Ilka, Zhuang, Yuan   +20 more
core   +2 more sources

Computational prediction and experimental validation of Ciona intestinalis microRNA genes

BMC Genomics, 2007
Background This study reports the first collection of validated microRNA genes in the sea squirt, Ciona intestinalis. MicroRNAs are processed from hairpin precursors to ~22 nucleotide RNAs that base pair to target mRNAs and inhibit expression.
Pasquinelli Amy E, Holtz Janette, Norden-Krichmar Trina M, Gaasterland Terry   +3 more
doaj   +1 more source