Results 121 to 130 of about 2,780 (190)
Checkpoint kinase 1 (CHK1); protein CIP2A (KIAA1524; CIP2A) [PDF]
Science-Business eXchange, 2013 openaire +1 more source
A Systems Biology Analysis of PP2A Functions in Cancer Cells [PDF]
, 2017 Cancer is characterized by aberrant activation of phosphorylation signalling cascades. However, despite the critical role of phosphatases in protein phosphorylation, their contribution to cancer cell signalling is only emerging.
Kauko, Otto
core
Cell microarray (CMA) : a novel screening method for prognostic factors in head and neck squamous cell carcinoma [PDF]
, 2018 Pään ja kaulan alueen levyepiteelisyöpä on yksi yleisimmistä syöpätyypeistä, muta sillä on silti yhä verrattain huono ennuste muihin yleisiin syöpätyyppeihin verrattuna.
Suvila, Karri
core
Zhongshan Daxue xuebao. Yixue kexue ban, 2018 【目的】探讨shRNA介导的CIP2A基因表达对肠癌HT29细胞生物学特性的影响。【方法】采用RTPCR及Westernblot检测重组质粒转染肠癌HT29细胞前后mRNA和蛋白的变化；分别采用CCK8、Transwell小室 法、流式细胞术及裸鼠成瘤实验（n＝20）测定其对肠癌HT29细胞增殖、克隆形成、凋亡及侵袭能力的影响。【结 果】shRNA-CIP2A转染肠癌HT29细胞后，肠癌HT29细胞内CIP2AmRNA和蛋白的表达明显下降。实验组肠癌 HT29细胞增殖明显受到抑制 ...
梁景琳 +3 more
doaj
Clinical Research Progress of Cancer Axis CIP2A
Advances in Clinical Medicine, 2021 openaire +1 more source
DP133 | CIP2A IS IMPLICATED IN RUXOLITINIB RESISTANCE IN MYELOFIBROSIS
HaematologicaAlthough ruxolitinib (Ruxo) is the standard of care for patients (pts) with myelofibrosis (MF), therapeutic resistance develops in approximately 50% within 3-5 years, posing a clinical challenge.
M. Balliu +6 more
doaj
UCHL1 Promotes Gastric Cancer Progression by Regulating CIP2A Degradation. [PDF]
Pharmaceuticals (Basel)Lee GY +4 more
europepmc +1 more source
The Prognostic Value of CIP2A and Its Association with CD31, E-Cadherin, and pAMPK in Lung Cancer. [PDF]
Int J Mol SciLee PY +5 more
europepmc +1 more source
CIP2A interacts with AKT1 to promote the malignant biological behaviors of oral squamous cell carcinoma by upregulating the GSK‑3β/β‑catenin pathway. [PDF]
Exp Ther Med, 2023 Che Y, Zhang H, Li H, Wu X.
europepmc +1 more source