Results 11 to 20 of about 33,669 (192)

Successful Management of a Complicated Forearm Fracture in a Patient with Congenital Insensitivity to Pain: A Case Report [PDF]

International Medical Case Reports Journal
Anas Alrusan,1 Suhaib Bani Essa,2 Saif Aldin Naif Rawabdeh,3 Yazan Anaqreh,2 Modather Hatamleh,1 Mohammad Alradaideh,1 Mohammed Baker,4 Abdelwahab Aleshawi4 1Department of Anesthesiology, Faculty of Medicine, Jordan University of Science and Technology ...
Alrusan A, Bani Essa S, Rawabdeh SAN, Anaqreh Y, Hatamleh M, Alradaideh M, Baker M, Aleshawi A   +7 more
doaj   +2 more sources

PREFACE: PROGRESS AND PROSPECTS OF RESEARCH AND PRACTICE OF DIGITAL CULTURAL HERITAGE [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2021
Co-hosted by Tsinghua University, ICOMOS China, Tsinghua Heritage Institute for Digitization, and Beijing University of Civil Engineering and Architecture, the CIPA2021 symposium (28th biennial symposium of the international scientific committee for ...
A. Dang
doaj   +3 more sources

Congenital Insensitivity to Pain and Anhidrosis With Orthopedic and Self‐Injury Complications in a 5‐Year‐Old Boy: A Case Report [PDF]

Clinical Case Reports
Congenital insensitivity to pain with anhidrosis (CIPA) is a rare autosomal recessive disorder because of NTRK1 gene mutations, leading to an inability to perceive pain and temperature and lack of sweating. Its rarity and unique clinical challenges, such
Zubair Amin, Humza Saeed, Syed Imam Naufil, Sadaf Saba, Abdullah Imtiaz, Syed Hassan Akhlaq, Muhammad Husnain Ahmad, Masab Ali   +7 more
doaj   +2 more sources

Reassessing the Conduct of Patch Clamp Cardiac Ion Channel Assays to Improve Nonclinical Data Translation to Clinical ECG Changes and Proarrythmia Risk. [PDF]

Clin Transl Sci
ABSTRACT The Comprehensive in vitro Proarrhythmia Assay (CiPA) initiative proposes integrating multi‐cardiac ion channel pharmacology to improve the prediction of drug‐induced Torsade de Pointes (TdP) risk. However, several studies under CiPA have demonstrated misalignment between nonclinical and clinical data.
Alvarez Baron C, Zhao J, Guo D, Mistry S, De Palma R, Ismaiel OA, Wu WW.   +6 more
europepmc   +2 more sources

CipA mediates complement resistance of Acinetobacter baumannii by formation of a factor I-dependent quadripartite assemblage

Frontiers in Immunology, 2022
Multidrug-resistant Acinetobacter baumannii is known to be one of the leading pathogens that cause severe nosocomial infections. To overcome eradication by the innate immune system during infection, A.
Julia I. Ries, Marie Heß, Noura Nouri, Thomas A. Wichelhaus, Stephan Göttig, Franco H. Falcone, Peter Kraiczy   +6 more
doaj   +1 more source

Congenital Insensitivity to Pain With Anhidrosis: First Reported Case in Nepal. [PDF]

Clin Case Rep
ABSTRACT Congenital insensitivity to pain with anhidrosis is a rare autosomal recessive disorder characterized by anhidrosis, self‐mutilation, and insensitivity to pain and temperature. While genetic testing confirms the diagnosis, it is not always feasible, making clinical recognition crucial in resource‐limited settings.
Pant S, Adhikari D, Pandey P, Bajracharya B, Sharma R.   +4 more
europepmc   +2 more sources

Manifestaciones clínicas de la insensibilidad congénita al dolor con anhidrosis

Salud Uninorte, 2020
Introducción: La insensibilidad congénita al dolor con anhidrosis (HSAN IV o CIPA) es una enfermedad rara con sintomatologia multisistémica, que impacta el funcionamiento cognitivo, y afecta negativamente la calidad de vida los pacientes y sus familias.
YANIN ELENA SANTOYA MONTES, PEDRO PUENTES ROZO   +1 more
doaj   +1 more source

Identification of founder and novel mutations that cause congenital insensitivity to pain (CIP) in palestinian patients

BMC Medical Genomics, 2023
Background Congenital insensitivity to pain (CIP) is a rare autosomal recessive disorder characterized primarily by an inability to perceive physical pain from birth, resulting in the accumulation of bruising, inflammation, and fractures that affect ...
Boushra Khaled, Mahmoud Alzahayqa, Ahmad Jaffal, Husam Sallam, Rua’a Thawabta, Mamoun Mansour, Akram Alian, Zaidoun Salah   +7 more
doaj   +1 more source

Anesthetic management of a child with congenital insensitivity to pain with anhidrosis: A case report

Frontiers in Surgery, 2022
Congenital insensitivity to pain with anhidrosis (CIPA) is a rare, autosomal recessive disease classified as hereditary sensory and autonomic neuropathy type VI. Patients with CIPA are characterized by insensitivity to pain, episodes of unexplained fever,
Ying Zhang, Zhiyu Geng
doaj   +1 more source

Novel Gross Deletion Mutations in NTRK1 Gene Associated With Congenital Insensitivity to Pain With Anhidrosis

Frontiers in Pediatrics, 2021
Background: Congenital insensitivity to pain with anhidrosis (CIPA) is a rare inherited autosomal recessive disorder characterized by insensitivity to noxious stimuli, anhidrosis, recurrent fever, and intellectual disability.
Lulu Li, Chao Jia, Yue Tang, Yuanyuan Kong, Yaofang Xia, Li Ma   +5 more
doaj   +1 more source