Results 91 to 100 of about 130,132 (369)
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
PUP Journal of Science and Technology, 2018 The researcher has recently been working on the authenticity of information particularly with the use of cryptographic hash functions such as MD5 and Secure Hash Algorithm (SHA).
Francis G. Balazon
doaj +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Matematika, 2018 Abstrak. Kriptografi polyalphabetic merupakan improvisasi dari teknik substitusi monoalphabetic. Polyalphabetic substitution chiper melakukan teknik kriptografi monoalphabetic satu kali proses untuk suatu plainteks pesan.
Yurika Permanasari, Erwin Harahap
doaj +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
The Methods of Information Security Based on Blurring of System
Безопасность информационных технологий, 2016 The paper present the model of researching system with own known input, output and set of discrete internal states. These theoretical objects like an absolutely protected from research system and an absolutely indiscernible data transfer channel are ...
Mikhail Andreevich Styugin
doaj
International Journal of Population Data Science, 2017 Objectives To use routinely collected datasets and data linkage to identify patterns of healthcare utilisation by children and young people (CYP) with adolescent mental health (AMH) disorders across the four UK Nations, with a particular focus on self ...
Sophie Wood +4 more
doaj +1 more source
A note on some algebraic trapdoors for block ciphers
, 2018 We provide sufficient conditions to guarantee that a translation based cipher is not vulnerable with respect to the partition-based trapdoor. This trapdoor has been introduced, recently, by Bannier et al.
Calderini, Marco
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