Results 101 to 110 of about 130,132 (369)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
About the Soviet Cryptographs Contribution on the Victory by Moscow
Безопасность информационных технологий, 2011 On December 5, 2011, we mark the 70th anniversary of the first great defeat on the fascist Germany during the Soviet troops’ counter-offensive of Moscow, which has become the first step towards to the Victory Day.
D. A. Larin
doaj
Stream cipher based on quasigroup string transformations in $Z_p^*$
, 2004 In this paper we design a stream cipher that uses the algebraic structure of the multiplicative group $\bbbz_p^*$ (where p is a big prime number used in ElGamal algorithm), by defining a quasigroup of order $p-1$ and by doing quasigroup string ...
Gligoroski, Danilo
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
An algorithm for computing the upper bound for non-minimum weight differentials in 2-round LSX-ciphers [PDF]
, 2021 Vitalii Aleksandrovich Kiryukhin
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Features of Structural Hardware Transformation of Information in Cryptosystems
Doklady Belorusskogo gosudarstvennogo universiteta informatiki i radioèlektronikiThe article considers types, functions and some features of cryptosystems, as well as circuit design options for expanding their functionality. Options for generating keys and ciphers used in cryptosystems with a typical structural organization, and ...
A. F. Chernyavskiy +2 more
doaj +1 more source
Modern Crypto-Analysis of Polyalphabetic Ciphers Using a Genetic Algorithm
, 2015 This project involved implementing a genetic algorithm to help automate the crypto-analysis of the Vigenere ...
Heald, Benjamin E.
core