Results 201 to 210 of about 87,772 (336)

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

A Programmed DNA Dynamic Assembly-Guided Molecular Amplifier for Authentic Information Decryption. [PDF]

Adv Sci (Weinh)
Yang N, Zhou J, Yuan F, Liu Y, Zhang J, Zhuo Y, Ouyang Y, Chai Y, Zhang P, Yuan R.   +9 more
europepmc   +1 more source

Modes of Operation of Stream Ciphers

, 2001
Jovan Dj. Golić
openalex   +1 more source

A highly efficient AES cipher chip [PDF]

, 2003
Chih-Pin Su, Tsung-Fu Lin, Chih-Tsun Huang, Cheng‐Wen Wu   +3 more
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Cascading quantum walks with Chebyshev map for designing a robust medical image encryption algorithm. [PDF]

Sci Rep
Alblehai F, El-Latif AAA, Pławiak P, Abd-El-Atty B.   +3 more
europepmc   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Diagnostic MicroRNA Signatures to Support Classification of Pulmonary Hypertension. [PDF]

Circ Genom Precis Med
Errington N, Zhou L, Rhodes CJ, Fong YL, Zhou L, Kariotis S, Harder E, Waxman A, Jatkoe T, Wharton J, Thompson AAR, Condliffe RA, Kiely DG, Howard LS, Toshner M, He C, Wang D, Wilkins MR, Lawrie A.   +18 more
europepmc   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Integrity verified lightweight ciphering for secure medical image sharing between embedded SoCs. [PDF]

Sci Rep
Janakiraman S, R VR, Sivaraman R, Sridevi A, Upadhyay HN, Amirtharajan R.   +5 more
europepmc   +1 more source