Results 201 to 210 of about 133,735 (361)
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Secure authentication using a multidimensional retinal biometric encryption method. [PDF]
Sci RepBanu Y, Rath BK, Gountia D.
europepmc +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Dynamics analysis of a four-dimensional hyperchaotic hidden system and its application in image encryption. [PDF]
Sci RepYu Z +8 more
europepmc +1 more source
, 1937 Experience has shown and the point is forcibly expressed by Yves Gylden, in his "'The Contributions of the Cryptographic Bureaus in the World War", that at leatst an elementary knowledge of cryptanalysis is prerequisite to intelligent cryptography. Those who are responsible for the promulgation of our codes and ciphers, as well as for the promulgation ...
openaire +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Secure image encryption using a 4D chaotic system and Langton's ant cellular automaton. [PDF]
Sci RepAlshehri H.
europepmc +1 more source
Correlation distribution for the horizontal orientation of the cipher Chair image.
Nasreen Zulfiqar (21601226) +7 more
openalex +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source