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Transintestinal Elimination of Ciprofloxacin
Chemotherapy, 1990This study identified the routes of elimination of ciprofloxacin in two groups of five subjects each: one of healthy volunteers; the other of patients with severe renal failure having mean creatinine clearance of 12 ml/min (range, 8-16 ml/min). Each subject received one dose of 200 mg ciprofloxacin infused intravenously (IV) over 30 min.
Hans Joachim Dr. Scholl+7 more
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Intraperitoneal penetration of ciprofloxacin
European Journal of Clinical Microbiology, 1986Ciprofloxacin, a quinolone derivative of carboxylic acid, has a spectrum of antimicrobial activity that includes the Enterobacteriaceae, Staphylococcus aureus and Pseudomonas aeruginosa (1). It may therefore prove useful, alone or in combination, in the prophylaxis or treatment of infections in patients undergoing abdominal surgery. Intraperitoneal and
R. Waldron+3 more
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Ciprofloxacin as Treatment for Conjunctivitis
Journal of Chemotherapy, 2004The authors studied the bactericidal action and therapeutic effectiveness of ciprofloxacin in treating external ocular infections (bacterial conjunctivitis and bacterial blepharoconjunctivitis). 108 ambulatory patients with clinical signs of conjunctivitis and blepharoconjunctivitis were enrolled in the study. All subjects underwent a conjunctival swab
CHISARI, Giuseppe, Reibaldi, Michele
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Ciprofloxacin Crystal Nephropathy
American Journal of Kidney Diseases, 2007Ciprofloxacin is a widely used fluoroquinolone for the treatment of patients with complicated and uncomplicated infections. With rare exceptions, only immune-mediated interstitial nephritis was described, with direct renal damage reported only in case of overdose.
STRATTA, Piero+4 more
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Ciprofloxacin in typhoid fever
The Indian Journal of Pediatrics, 1991The study covers 78 children with typhoid fever who were hospitalized in April & May 1990. Serious complications were present in 32% (toxemia 22%, ileus 25% and myocarditis 8%). Blood cultures were positive in 30 of 49 tested. Others were diagnosed by positive Widal test. In vitro cultures of S. typhi were resistant to chloramphenicol (90%), ampicillin
Ashish Bavdekar+3 more
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Oral Ciprofloxacin for Osteomyelitis
Orthopedics, 1990ABSTRACT: Ciprofloxacin is a new, oral, broad spectrum fluoroquinolone antibiotic which has a long serum half-life, a low incidence of significant adverse reactions, and is administered twice daily. Eighteen patients with osteomyelitis were treated with ciprofloxacin, 750 mg orally twice daily. The mean age of the patients was 43 years (range, 21 to 73
Amy L. Graziani+2 more
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Effect of ciprofloxacin on phagocytosis
European Journal of Clinical Microbiology, 1985Certain aspects of the relationship between host defence mechanisms and the new quinoline derivative ciprofloxacin in comparison to norfloxacin and ofloxacin were studied. Ciprofloxacin did not affect chemotaxis of human polymorphonuclear leucocytes in agarose.
P. I. Bergkvist, Arne Forsgren
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Renal elimination of sulfo-ciprofloxacin, a new metabolite of ciprofloxacin [PDF]
G. Höffken, Klaus Borner, Hartmut Lode
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