Results 91 to 100 of about 670 (182)

Perioperative dexmedetomidine effects on delirium in elderly patients after noncardiac surgery: A retrospective propensity score analysis [PDF]

BackgroundDelirium is a complex syndrome with limited pharmacological treatment options, whereas non-pharmacological prevention strategies warrant further investigation.
Han-Wen Gu, Hong-Wei Wang, Jian-Jun Yang, Liang Zang, Lin-Na Chen, Long He, Ming Cheng, Qian He, Qin-Jun Chu, Ze-Fei Zhu, Ze-Ping Li   +10 more
core   +1 more source

Comparative efficacy and safety of ciprofol, propofol, and propofol and etomidate mixture, and ciprofol and etomidate mixture in patients undergoing painless gastroscopy: A randomized, double-blind controlled clinical trial

Medicine
Background: To compare the efficacy and safety of ciprofol, propofol, propofol and etomidate mixture or ciprofol and etomidate mixture in patients undergoing painless gastroscopic anesthesia, and to explore the optimal plan to relieve the patient’s discomfort.
Yanlong Liu, Yihong Qian, Lilan Zhang, Shanliang Guo, Longcheng Fan, Mingsheng Zhang, Zhongyu Liu   +6 more
openaire   +2 more sources

Effects of ciprofol infusion on hemodynamics during induction and maintenance of anesthesia and on postoperative recovery in patients undergoing thoracoscopic lobectomy: Study protocol for a randomized, controlled trial.

PLoS ONE
IntroductionCiprofol, a new candidate drug, is effective and safe for the maintenance of anesthesia in non-cardiothoracic and non-neurological elective surgery.
Na Guo, Jianqiao Cao, Mingjie Duan, Fei Zhou, Wei Wang, Lingling Xu, Chuansong Wei, Xiumei Song   +7 more
doaj   +1 more source

Exhaled propofol monitoring for plasma drug prediction in rats [PDF]

While propofol can be detected in exhaled breath in rats, robust evidence supporting its correlation with plasma concentrations or its use in predicting plasma levels remains lacking. In this study, eighteen mechanically ventilated rats were divided into
Pan Chang, Pan Chang, Wensheng Zhang, Wensheng Zhang, Xiaoxiao Li, Xiaoxiao Li, Xing Liu, Xing Liu, Yi Kang, Yi Kang, Yixiang Duan, Zhongjun Zhao   +11 more
core   +1 more source

Ciprofol vs propofol for gastrointestinal endoscopy sedation: a systematic review and meta-analysis

International Journal of Surgery
Background: Ciprofol, a propofol derivative, is increasingly used for sedation in China. However, the specific benefits of ciprofol in gastrointestinal endoscopic sedation have not been fully evaluated. This meta-analysis aimed to compare the efficacy and safety of ciprofol with propofol in gastrointestinal ...
Yu, Yunfeng, Deng, Juan, Yin, Yuman, Yang, Xinyu, Liao, Min, Yu, Rong   +5 more
openaire   +3 more sources

Efficacy and Safety of Ciprofol Versus Propofol as Anesthetic for Patients Undergoing Painless Colonoscopy

Pain and Therapy
Ciprofol is a novel propofol analogue with a characteristic of hemodynamic stability. At present, there is a lack of research comparing the hemodynamic stability of ciprofol and propofol during painless colonoscopy. In this study, we aim to test the hypothesis that ciprofol is superior to propofol in terms of hemodynamic stability for sedation ...
Ke Qiang He, Ting Ting Huang, Meng Yuan Tan, Chen Gao, Sheng Wang   +4 more
openaire   +3 more sources

Effect of Lidocaine on Ciprofol Dosage and Efficacy in Patients Who Underwent Gastroscopy Sedation

Medical Science Monitor Basic Research
BACKGROUND Intravenous ciprofol is a short-acting sedative with minimal respiratory and circulatory suppression and limited analgesia. Intravenous lidocaine provides analgesia during surgical procedures. This study included 70 patients who underwent gastroscopy with analgesia and aimed to evaluate the effects of intravenous lidocaine on the dose of ...
Han, Yang, Zhang, Baohua, Jin, Li, Yu, Zhiyang, He, Huan   +4 more
openaire   +2 more sources

Efficacy and safety of ciprofol for sedation/anesthesia in patients undergoing hysteroscopy: a prospective, randomized, non-inferiority trial

Annals of Medicine
Introduction Propofol is the preferred sedative for painless hysteroscopy and other procedures due to its fast onset and short duration. However, its limitations, including injection pain, respiratory depression, blood pressure decline, and bradycardia ...
Shi Cheng, Haixuan Wu, Zhongqi Liu, Dan Liu, Minghui Cao, Ganglan Fu   +5 more
doaj   +1 more source

Early sedation using ciprofol for intensive care unit patients requiring mechanical ventilation: a pooled post-hoc analysis of data from phase 2 and phase 3 trials

Annals of Intensive Care
Background Ciprofol was approved for use in intensive care unit (ICU) patients requiring sedation during mechanical ventilation in July 2022. A pooled post-hoc analysis of phase 2 and phase 3 trials was conducted primarily to explore hypotension-free ...
Yongjun Liu, Lingyun Zuo, Xiaoyun Li, Yao Nie, Chuanxi Chen, Ning Liu, Minying Chen, Jianfeng Wu, Xiangdong Guan   +8 more
doaj   +1 more source

Effect of remimazolam besylate versus midazolam on time to extubation in critically ill, mechanically ventilated patients: a randomized controlled trial [PDF]

BackgroundPrevious studies have indicated that the administration of short-acting sedatives prior to weaning from mechanical ventilation is linked to a more rapid recovery and extubation process, in addition to lowering intensive care unit (ICU ...
Aiguang Li, Binxiao Su, Chengli Wang, Guangcai Feng, Guangming Wang, Guifen Gan, Hao Guo, Jiang Li, Ning Xu, Qingxia Yuan, Renhuai Liu, Wenping Zheng, Xijing Zhang, Yu Chen   +13 more
core   +1 more source