Results 131 to 140 of about 736 (146)

Comparison of ciprofol (HSK3486) versus propofol for the induction of deep sedation during gastroscopy and colonoscopy procedures: A multi‐centre, non‐inferiority, randomized, controlled phase 3 clinical trial

Basic and Clinical Pharmacology and Toxicology, 2022
Abstract Ciprofol is a propofol analogue with improved pharmacokinetic properties. A multi‐centre, non‐inferiority trial was conducted to compare the deep sedation properties of ciprofol and propofol with a non‐inferiority margin of 8% in patients undergoing gastroscopy and colonoscopy.
Ya-Ping Wang, Shanglong Yao, Wen Ouyang   +2 more
exaly   +2 more sources

Comparative effective dose of ciprofol and propofol in suppressing cardiovascular responses to tracheal intubation

Scientific Reports
Ciprofol, a novel γ-aminobutyric acid receptor agonist, outperforms propofol with minimal cardiovascular effects, higher potency, reduced injection pain, and a broader safety margin.
Jia-Ning Hu, Tang‑yuan‑meng Zhao, Xiao-Ru Wu, Xing-Zhou Lin, Hu Sun, Min Liao   +5 more
exaly   +2 more sources

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Efficacy and safety of ciprofol for the sedation/anesthesia in patients undergoing colonoscopy: Phase IIa and IIb multi-center clinical trials

European Journal of Pharmaceutical Sciences, 2021
Ya-Ping Wang, Shanglong Yao, Wen Ouyang   +2 more
exaly  

Efficacy and safety of Ciprofol for procedural sedation and anesthesia in non-operating room settings

Journal of Clinical Anesthesia, 2023
Zhiyi Zuo, Xining Zhao
exaly  

Efficacy and safety of ciprofol (HSK3486) for procedural sedation and anesthesia induction in surgical patients: A systematic review and meta-analysis

Heliyon, 2023
Xin Liu, Jiaxuan Wen, Xiuhong Wei
exaly  

A preclinical study on online monitoring of exhaled ciprofol concentration by the ultraviolet time-of-flight spectrometer and prediction of anesthesia depth in beagles

Journal of Pharmaceutical and Biomedical Analysis, 2023
Zhongjun Zhao, Wensheng Zhang, Pan Chang   +2 more
exaly  

The Effect of Different Doses of Ciprofol in Patients with Painless Gastrointestinal Endoscopy

Drug Design, Development and Therapy, 2023
Xue-Ke Du
exaly  

Ciprofol: A Novel Medication from Development towards Clinical Use

Translational Perioperative and Pain Medicine, 2021
exaly  

The efficacy and safety of remimazolam besylate, ciprofol, and propofol during hysteroscopy

Frontiers in Pharmacology
Haiyan Lan, Qiaomin Xu
exaly  

Ciprofol is primarily glucuronidated by UGT1A9 and predicted not to cause drug-drug interactions with typical substrates of CYP1A2, CYP2B6, and CYP2C19

Chemico-Biological Interactions
Eric Chun Yong Chan, Jianjun Yang, Shuaibing Liu   +2 more
exaly