Results 251 to 260 of about 396,990 (333)

Collagen V Influences Homeostatic Maintenance of Patellar Tendon Failure Properties in Mature Female Mice

open access: yesJournal of Orthopaedic Research, EarlyView.
ABSTRACT The collagenous matrix of tendon provides mechanical integrity, allowing the tissue to withstand large tensile forces. While collagen I‐containing fibrils provide the major backbone of the tendon matrix, interactions with other collagen types are critical for matrix formation and maintenance.
Ryan J. Leiphart   +8 more
wiley   +1 more source

Examining the between‐ and within‐person associations among perceived sleep quality and mental health symptoms in emergency medical service clinicians

open access: yesJournal of Traumatic Stress, EarlyView.
Abstract Disturbed sleep is a known risk factor for heightened mental health symptoms, and this association may be particularly problematic among emergency medical service (EMS) clinicians. Yet, associations between daily sleep quality and daily mental health symptoms are understudied among this vulnerable group.
Enzo G. Plaitano   +7 more
wiley   +1 more source

USP28 Promotes Osimertinib Resistance in H1975 NSCLC Cells by Deubiquitinating and Stabilizing SIRT1

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osimertinib (OSI) resistance in non‐small cell lung cancer (NSCLC) remains a significant challenge. This report explored the precise role of USP28 on OSI resistance in NSCLC and identified a functional downstream effector. OSI‐resistant H1975 cells (H1975/OSI) were established by long‐term OSI exposure.
Hu‐Sen Fan   +4 more
wiley   +1 more source

Impact of Baseline Nutritional Status, Psychological Health, Fatigue, and Insomnia on Outcomes of Immune Checkpoint Inhibitors in Advanced Non‐Small Cell Lung Cancer: A Retrospective Cohort Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study investigated the impact of pretreatment nutritional status, psychological health, fatigue, and insomnia on outcomes of immune checkpoint inhibitors (ICIs) monotherapy in patients with advanced non‐small cell lung cancer (NSCLC). A total of 80 patients with stage IV NSCLC were enrolled.
Yu‐Xuan Zhu   +2 more
wiley   +1 more source

Reconstructed cell-type-specific rhythms in human brain link Alzheimer's pathology, circadian stress, and ribosomal disruption. [PDF]

open access: yesNeuron
Hollis HC   +9 more
europepmc   +1 more source

Contact‐dependent iron uptake from dust revealed by elemental analysis of single Trichodesmium colonies

open access: yesLimnology and Oceanography, EarlyView.
Abstract Aerosol dust deposited on the nutrient‐deprived surface ocean can boost phytoplankton growth and oceanic carbon uptake. Low mineral solubility restricts the biological utilization of dust‐nutrients, thereby benefiting phytoplankton that actively dissolve dust.
Yeala Shaked   +9 more
wiley   +1 more source

An ecological framework for microbial metabolites in the ocean ecosystem

open access: yesLimnology and Oceanography Letters, EarlyView.
Abstract The ocean microbe‐metabolite network involves thousands of individual metabolites that encompass a breadth of chemical diversity and biological functions. These microbial metabolites mediate biogeochemical cycles, facilitate ecological relationships, and impact ecosystem health. While analytical advancements have begun to illuminate such roles,
Bryndan P. Durham   +24 more
wiley   +1 more source

Home - About - Disclaimer - Privacy