Results 121 to 130 of about 485,259 (393)

Intestinal Clock Promotes Cognitive Memory Through Adenosine Signaling

open access: yesAdvanced Science, EarlyView.
The intestinal clock controls the expression of an adenosine enzyme that modulates systemic adenosine level and A1R signaling in the hippocampus, and in turn, cognitive function involving long‐term potentiation and BDNF‐dependent synaptic changes.
Min Chen   +13 more
wiley   +1 more source

The influence of biological rhythms on host–parasite interactions [PDF]

open access: yes, 2015
Biological rhythms, from circadian control of cellular processes to annual cycles in life history, are a main structural element of biology. Biological rhythms are considered adaptive because they enable organisms to partition activities to cope with ...
Helm, Barbara, Martinez-Bakker, Micaela
core   +1 more source

Smooth-muscle BMAL1 participates in blood pressure circadian rhythm regulation.

open access: yesJournal of Clinical Investigation, 2015
As the central pacemaker, the suprachiasmatic nucleus (SCN) has long been considered the primary regulator of blood pressure circadian rhythm; however, this dogma has been challenged by the discovery that each of the clock genes present in the SCN is ...
Zhongwen Xie   +9 more
semanticscholar   +1 more source

Circadian Rhythms in Immunity [PDF]

open access: yesCurrent Allergy and Asthma Reports, 2020
This review is focused on the existing evidence for circadian control of innate and adaptive immune responses to provide a framework for evaluating the contributions of diurnal rhythms to control of infections and pathogenesis of disease.Circadian rhythms driven by cell-autonomous biological clocks are central to innate and adaptive immune responses ...
openaire   +3 more sources

Bioinspired Prolactin Pulse Release from Responsive Microneedles for Inhibiting Fatty Liver Formation

open access: yesAdvanced Science, EarlyView.
Inspired by the prolactin secretion profile under normal physiological conditions, biomimetic prolactin‐releasing microneedles are designed. Under the control of near infrared (NIR), these responsive microneedles facilitate pulsed release of prolactin to inhibit fatty liver formation.
Hongli Yin   +6 more
wiley   +1 more source

Aβ-induced degradation of BMAL1 and CBP leads to circadian rhythm disruption in Alzheimer’s disease

open access: yesMolecular Neurodegeneration, 2015
Patients with Alzheimer’s disease (AD) frequently experience disruption of their circadian rhythms, but whether and how circadian clock molecules are perturbed by AD remains unknown. AD is an age-related neurological disorder and amyloid-β (Aβ) is one of
Hyundong Song   +8 more
semanticscholar   +1 more source

Adverse Cardiovascular Risk Profile and Increased Diurnal Salivary Cortisol in Girls With Turner Syndrome: An Exploratory Study

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Patients with Turner Syndrome (TS) and those exposed to high concentrations of glucocorticoids have a number of characteristics in common, including an increased risk of cardiovascular disease. Pediatric TS patients underwent studies of salivary cortisol (SC) and cortisone (SCn), body composition, continuous glucose monitoring, vascular ...
Lily Jones   +6 more
wiley   +1 more source

Circadian Rhythm, Lifestyle and Health: A Narrative Review

open access: yesIranian Journal of Public Health, 2018
Background: The circadian rhythm regulation plays a crucial role in people`s healthy lives affected by factors consisting of cosmic events related to the universe and earth, environmental factors (light, night and day duration, seasons) and lifestyles ...
Dariush FARHUD, Zahra ARYAN
doaj  

Naturally occurring circadian rhythm and sleep duration are related to executive functions in early adulthood [PDF]

open access: yes, 2017
Experimental sleep deprivation studies suggest that insufficient sleep and circadian misalignment associates with poorer executive function. It is not known whether this association translates to naturally occurring sleep patterns. A total of 512 of full-
Banks   +39 more
core   +2 more sources

The development and course of bipolar spectrum disorders: an integrated reward and circadian rhythm dysregulation model.

open access: yesAnnual Review of Clinical Psychology, 2015
In this article, we present and review the evidence for two major biopsychosocial theories of the onset and course of bipolar spectrum disorders (BSDs) that integrate behavioral, environmental, and neurobiological mechanisms: the reward hypersensitivity ...
L. Alloy, R. Nusslock, Elaine M Boland
semanticscholar   +1 more source

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