Results 151 to 160 of about 492,257 (392)

Circadian rhythms [PDF]

open access: yesFEBS Letters, 2011
Michael Brunner, Martha Merrow
openaire   +2 more sources

Structural Basis of GABAB Receptor Activation during Evolution

open access: yesAdvanced Science, EarlyView.
This study explores the structural and functional mechanisms of the drosophila GABAB receptor, a key role in neurotransmission. Using cryo‐EM, the research reveals how the receptor's activation differs from its human counterpart, highlighting unique evolutionary features.
Guofei Hou   +14 more
wiley   +1 more source

Detection and Analysis of Circadian Biomarkers for Metabolic Syndrome Using Wearable Data: Cross-Sectional Study

open access: yesJMIR Medical Informatics
BackgroundWearable devices are increasingly used for monitoring health and detecting digital biomarkers related to chronic diseases such as metabolic syndrome (MetS).
Jeong-Kyun Kim, Sujeong Mun, Siwoo Lee
doaj   +1 more source

Development of salivary cortisol circadian rhythm in preterm infants.

open access: yesPLoS ONE, 2017
ObjectivesTo investigate at what age preterm infants develop a salivary cortisol circadian rhythm and identify whether it is dependent on gestational age and/or postnatal age.
Katrin Ivars   +5 more
doaj   +1 more source

Mouse circadian plasma leptin and active ghrelin rhythms under ad libitum and scheduled feeding [PDF]

open access: yes, 2007
Thesis (M.S.) University of Alaska Fairbanks, 2007Light is the strongest timing cue for the circadian system, but non-photic cues can also entrain the master circadian clock, i.e., suprachiasmatic nuclei (SCN).
Wan, Haiting
core  

Eyeless Mexican Cavefish Save Energy by Eliminating the Circadian Rhythm in Metabolism

open access: yesPLoS ONE, 2014
The eyed surface form and eyeless cave form of the Mexican tetra Astyanax mexicanus experience stark differences in the daily periodicities of light, food and predation, factors which are likely to have a profound influence on metabolism. We measured the
D. Moran, Rowan Softley, E. Warrant
semanticscholar   +1 more source

A Single‐Molecule Pleuripotent Scaffold for Combinational Therapy of Alzheimer's Disease via Intranasal Administration

open access: yesAdvanced Science, EarlyView.
Herein, guanidinium‐modified calix[5]arene (GC5AY) is developed featuring small size, positive charge, and desirable amphiphilicity, that can efficiently traverse the nasal mucosal barrier for brain drug delivery. Additionally, possessing inherent therapeutic functions, GC5AY can thus serve as a single‐molecule pleuripotent scaffold for multi‐target ...
Jian‐Mei Gao   +11 more
wiley   +1 more source

Ageing and osteoarthritis: a circadian rhythm connection

open access: yesBiogerontology (Dordrecht), 2014
Osteoarthritis (OA) is the most common joint disease, affecting articular cartilage of the joints, with currently no cure. Age is a major risk factor for OA, but despite significant advances made in the OA research field, how ageing contributes to OA is ...
N. Gossan, R. Boot-Handford, Q. Meng
semanticscholar   +1 more source

Bioinspired Engineering beyond Homeostasis

open access: yesAdvanced Intelligent Systems, EarlyView.
This perspective article introduces systems biology as the unifying theoretical framework behind bioinspired engineering. As an example, it explores how disruptions in multiscale biological systems, associated with pathological states, can be viewed as localized failure modes of biological cooperation showing emergent advantages that can inspire ...
Rosalia Moreddu
wiley   +1 more source

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