Results 151 to 160 of about 492,257 (392)
Structural Basis of GABAB Receptor Activation during Evolution
This study explores the structural and functional mechanisms of the drosophila GABAB receptor, a key role in neurotransmission. Using cryo‐EM, the research reveals how the receptor's activation differs from its human counterpart, highlighting unique evolutionary features.
Guofei Hou+14 more
wiley +1 more source
BackgroundWearable devices are increasingly used for monitoring health and detecting digital biomarkers related to chronic diseases such as metabolic syndrome (MetS).
Jeong-Kyun Kim, Sujeong Mun, Siwoo Lee
doaj +1 more source
Development of salivary cortisol circadian rhythm in preterm infants.
ObjectivesTo investigate at what age preterm infants develop a salivary cortisol circadian rhythm and identify whether it is dependent on gestational age and/or postnatal age.
Katrin Ivars+5 more
doaj +1 more source
Mouse circadian plasma leptin and active ghrelin rhythms under ad libitum and scheduled feeding [PDF]
Thesis (M.S.) University of Alaska Fairbanks, 2007Light is the strongest timing cue for the circadian system, but non-photic cues can also entrain the master circadian clock, i.e., suprachiasmatic nuclei (SCN).
Wan, Haiting
core
Eyeless Mexican Cavefish Save Energy by Eliminating the Circadian Rhythm in Metabolism
The eyed surface form and eyeless cave form of the Mexican tetra Astyanax mexicanus experience stark differences in the daily periodicities of light, food and predation, factors which are likely to have a profound influence on metabolism. We measured the
D. Moran, Rowan Softley, E. Warrant
semanticscholar +1 more source
Herein, guanidinium‐modified calix[5]arene (GC5AY) is developed featuring small size, positive charge, and desirable amphiphilicity, that can efficiently traverse the nasal mucosal barrier for brain drug delivery. Additionally, possessing inherent therapeutic functions, GC5AY can thus serve as a single‐molecule pleuripotent scaffold for multi‐target ...
Jian‐Mei Gao+11 more
wiley +1 more source
Circadian Rhythms and the Circadian Organization of Living Systems [PDF]
Colin S. Pittendrigh
openalex +1 more source
Ageing and osteoarthritis: a circadian rhythm connection
Osteoarthritis (OA) is the most common joint disease, affecting articular cartilage of the joints, with currently no cure. Age is a major risk factor for OA, but despite significant advances made in the OA research field, how ageing contributes to OA is ...
N. Gossan, R. Boot-Handford, Q. Meng
semanticscholar +1 more source
Bioinspired Engineering beyond Homeostasis
This perspective article introduces systems biology as the unifying theoretical framework behind bioinspired engineering. As an example, it explores how disruptions in multiscale biological systems, associated with pathological states, can be viewed as localized failure modes of biological cooperation showing emergent advantages that can inspire ...
Rosalia Moreddu
wiley +1 more source