Results 181 to 190 of about 328,367 (238)
The circadian rhythm of cholesterol biosynthesis in the salivary glands of the mice
, 1976 Haruo Nakamura +2 more
openalex +2 more sources
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 596-605, March 2025.ABSTRACT Linerixibat, an ileal bile acid transporter (IBAT) inhibitor, is being evaluated for the treatment of pruritus in primary biliary cholangitis (PBC). Diarrhea is commonly reported with this drug class as IBAT inhibition redirects bile acids (BA) to the colon.
Fernando Carreño +4 more
wiley +1 more source
Sleep and circadian rhythm regulation in early Parkinson disease.
JAMA Neurology, 2014 D. P. Breen +6 more
semanticscholar +1 more source
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT Congenital adrenal hyperplasia (CAH) is a genetic disorder characterized by impaired cortisol production and consequent elevated adrenocorticotropic hormone (ACTH): CAH patients often require lifelong hydrocortisone therapy. Disease severity reflects residual 21‐hydroxylase enzyme activity, crucial for cortisol synthesis.
Davide Bindellini +7 more
wiley +1 more source
Sustainable Development, EarlyView.ABSTRACT The design of lighting systems, has, in recent years, transcended the basic function of providing visibility, becoming a key component of promoting the health and well‐being of occupants by integrating biological, psychological, and energy aspects. The growing understanding of the effects of light on the circadian cycle has posed a fundamental
Lara Vélez González +3 more
wiley +1 more source
Small, EarlyView.NR1D1 suppresses epithelial CD47 transcription to promote efferocytosis by macrophages. In UC, NR1D1 expression is diminished, leading to CD47 upregulation, inhibition of apoptotic cell clearance, and exacerbation of intestinal inflammation. Restoring rhythmic NR1D1 activation using SR9011‐loaded bioadhesive hydrogel enhances efferocytosis, improves ...
Yidong Chen +7 more
wiley +1 more source
United European Gastroenterology Journal, EarlyView.ABSTRACT Introduction Abdominal distension is an objective visible sign of increased abdominal girth. Bloating is a feeling of abdominal fullness and discomfort. Bloating may be associated or not with abdominal distension. Bloating and abdominal distension are among the most commonly reported gastrointestinal symptoms and may be associated with both ...
Chloé Melchior +20 more
wiley +1 more source
Behavioural responses of brown bears to helicopter capture
Wildlife Biology, EarlyView.Understanding the effects of capture and handling on wild animals is crucial in evaluating ethical practices in ecological research, and in avoiding biased conclusions from misinterpreting biologging data potentially affected by capture. The aim of this study was to assess the effects of helicopter capture on the behaviour of Scandinavian brown bears ...
Alexandra Thiel +9 more
wiley +1 more source