Results 211 to 220 of about 492,257 (392)

A reciprocal interaction between L‐lysine and Holdemanella biformis modulates intestinal barrier function and anxiety in irritable bowel syndrome

open access: yesiMetaOmics, EarlyView.
This study uncovers a complex interaction between l‐lysine and Holdemanella biformis (H. biformis) in irritable bowel syndrome (IBS). l‐lysine enhances intestinal barrier function and alleviates anxiety‐like behaviours by modulating tryptophan metabolism. In contrast, H. biformis improves gut barrier integrity but exacerbates anxiety‐like behaviours. H.
Chun‐Hui Jiang   +9 more
wiley   +1 more source

The microbiome in cancer

open access: yesiMeta, EarlyView.
This comprehensive review elucidates the transformative role of the human microbiome in cancer biology, revealing innovative mechanistic insights into the intricate tumor–microbe interactions across diverse organ systems. This work highlights the clinical and translational value of novel microbiome‐based biomarkers for early detection, prognosis, and ...
Anqi Lin   +50 more
wiley   +1 more source

DESYNCHRONIZATION OF HUMAN CIRCADIAN RHYTHMS

open access: bronze, 1967
Jürgen Aschoff   +2 more
openalex   +2 more sources

Effects of 1267 nm Illumination on Microcirculation Regulatory Mechanisms

open access: yesJournal of Biophotonics, EarlyView.
The question of activation of blood flow regulatory mechanisms during laser illumination remains open to date. This study showed the effect of laser exposure on the microcirculatory bed, which appears in the form of endothelium‐dependent vascular activity.
Lyubov Eratova   +2 more
wiley   +1 more source

Evaluating the Role of PD1 and MTNR1B Gene Variants in Breast Cancer Susceptibility: A Case–Control Study in Bangladesh

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
The investigation revealed that the PD1 GG genotype exhibited a significant protective effect, substantially reducing the likelihood of breast cancer development. The genotype, CG of the MTNR1B gene, was connected with a lessened likelihood of breast cancer development, whereas the GG genotype showed no statistically significant correlation.
Farhan Jamil   +8 more
wiley   +1 more source

Saliva as a TDM matrix and its application in the model‐informed precision dosing

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract This study reviews the main points of saliva as a therapeutic drug monitoring (TDM) matrix, its advantages and limitations, the methods of saliva sample collection and testing, the types of drugs in saliva TDM, and the methods of establishing saliva population pharmacokinetic (Pop PK) models, as well as summarizes the experiences and ...
Baohua Xu   +9 more
wiley   +1 more source

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