Results 291 to 300 of about 492,257 (392)

Microbiota diversity and differences in the respiratory tract of children with pneumonia

open access: yesPediatric Investigation, EarlyView.
Differences in microbial communities in the upper and lower respiratory tract in patients with pneumonia were investigated in this study by sequencing the 16S rRNA genes in pharyngeal swabs and alveolar lavage fluid. Forty‐three subjects were enrolled in the study, and one upper and one lower respiratory tract sample were collected from each subject ...
Dandan Ge   +4 more
wiley   +1 more source

Effects of timed LED regimes on tomato plant traits, performance of two‐spotted spider mites, and predatory mites (Phytoseiulus persimilis)

open access: yesPest Management Science, Volume 81, Issue 4, Page 2300-2311, April 2025.
Light‐emitting diode (LED)‐based treatments for enhancing crop production and pest management have primarily focused on continuous treatments. This study, using Tetranychus urticae and Phytoseiulus persimilis, demonstrates that the timing of LED supplementation is crucial for designing integrated pest management strategies that improve both plant ...
Patrice Savi   +5 more
wiley   +1 more source

Analysis of C4 Concentrations to Predict Impact of Patient‐Reported Diarrhea Associated With the Ileal Bile Acid Transporter Inhibitor Linerixibat

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 596-605, March 2025.
ABSTRACT Linerixibat, an ileal bile acid transporter (IBAT) inhibitor, is being evaluated for the treatment of pruritus in primary biliary cholangitis (PBC). Diarrhea is commonly reported with this drug class as IBAT inhibition redirects bile acids (BA) to the colon.
Fernando Carreño   +4 more
wiley   +1 more source

Predicting Residual 21‐Hydroxylase Enzymatic Activity in Pediatric and Adult Congenital Adrenal Hyperplasia Patients: Towards Individualized Therapy

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Congenital adrenal hyperplasia (CAH) is a genetic disorder characterized by impaired cortisol production and consequent elevated adrenocorticotropic hormone (ACTH): CAH patients often require lifelong hydrocortisone therapy. Disease severity reflects residual 21‐hydroxylase enzyme activity, crucial for cortisol synthesis.
Davide Bindellini   +7 more
wiley   +1 more source

Advances in Atopic Dermatitis Treatment: From Pathogenesis to Natural Product‐Based Therapies

open access: yesPhytotherapy Research, EarlyView.
NPs improve atopic dermatitis mainly include flavonoids, phenols, glycosides, alkaloids, and others. ABSTRACT Atopic dermatitis (AD), a widespread and chronic inflammatory skin disorder, profoundly affects patients' quality of life, imposes significant psychological strain, and adds to the public health burden.
Xinyun Fan   +8 more
wiley   +1 more source

Night lights from space: potential of SDGSAT‐1 for ecological applications

open access: yesRemote Sensing in Ecology and Conservation, EarlyView.
Our study emphasizes the importance of advancing ALAN monitoring from space for ecology and conservation, and it highlights the novel opportunities of SDGSAT‐1. We discuss shortcomings that need to be resolved and identify promising avenues for sound ecological impact assessments of ALAN on ecosystems using space‐borne remote sensing.
Dominique Weber   +9 more
wiley   +1 more source

Neural circuitry of rapid eye movement sleep homeostasis: Mechanistic insights and pathological implications

open access: yesSleep Research, EarlyView.
Abstract Rapid eye movement (REM) sleep is a unique brain state crucial for emotion, memory, and plasticity. Unlike well‐understood non‐REM (NREM) sleep homeostasis, REM sleep homeostasis remains less clearly defined. This review highlights recent progress in understanding REM sleep homeostasis, focusing on its neurophysiological markers, neural ...
Ting He
wiley   +1 more source

European Consensus on Functional Bloating and Abdominal Distension—An ESNM/UEG Recommendations for Clinical Management

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Introduction Abdominal distension is an objective visible sign of increased abdominal girth. Bloating is a feeling of abdominal fullness and discomfort. Bloating may be associated or not with abdominal distension. Bloating and abdominal distension are among the most commonly reported gastrointestinal symptoms and may be associated with both ...
Chloé Melchior   +20 more
wiley   +1 more source

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