Results 91 to 100 of about 176,535 (378)

Management of rapid eye movement sleep behavior disorder in patients with Parkinson's disease [PDF]

open access: yes, 2016
Among all of the devastating effects that Parkinson’s disease (PD) has on an individual, sleep dysfunction is one that can have a profound effect on the entire family of the patient. The most potentially destructive of these sleep syndromes being that of
Jeffries, Michael
core   +1 more source

The influence of timeshift on ciradian rhythm of sensitivity to X-irradiation in mice [PDF]

open access: yes, 1984
For two groups of male C3H mice an eastbound transmeridional flight was simulated by inducing a time shift of the L:D schedule of 8 hr. The assumed flight brought about a maxima) reduction of the daily light and dark span, respectively.
Arbogast, B., Gerbes, Alexander L.
core   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

open access: yesAdvanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro   +6 more
wiley   +1 more source

Adaptive mechanisms of homeostasis disorders

open access: yesJournal of Education, Health and Sport, 2017
The ability to preserve a permanent level of internal environment in a human organism, against internal and external factors, which could breach the consistency, can be define as homeostasis.
Anna Maria Dobosiewicz   +5 more
doaj   +3 more sources

Metabolic Effects of Bariatric Surgery in Mouse Models of Circadian Disruption [PDF]

open access: yes, 2015
Background/Objectives: Mounting evidence supports a link between circadian disruption and metabolic disease. Humans with circadian disruption (for example, night-shift workers) have an increased risk of obesity and cardiometabolic diseases compared with ...
Arble, Deanna M.   +4 more
core   +3 more sources

Evaluation of circadian phenotypes utilizing fibroblasts from patients with circadian rhythm sleep disorders

open access: yesTranslational Psychiatry, 2017
We evaluated the circadian phenotypes of patients with delayed sleep–wake phase disorder (DSWPD) and non-24-hour sleep–wake rhythm disorder (N24SWD), two different circadian rhythm sleep disorders (CRSDs) by measuring clock gene expression rhythms in ...
A. Hida   +12 more
semanticscholar   +1 more source

Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC‐Derived Cortical Organoids

open access: yesAdvanced Science, EarlyView.
A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra   +23 more
wiley   +1 more source

Extreme morning chronotypes are often familial and not exceedingly rare: the estimated prevalence of advanced sleep phase, familial advanced sleep phase, and advanced sleep-wake phase disorder in a sleep clinic population. [PDF]

open access: yes, 2019
Study objectivesReport the first prevalence estimates of advanced sleep phase (ASP), familial advanced sleep phase (FASP), and advanced sleep-wake phase disorder (ASWPD).
Ashbrook, Liza H   +6 more
core  

Modeling circadian and sleep-homeostatic effects on short-term interval timing [PDF]

open access: yes, 2015
Short-term interval timing i.e., perception and action relating to durations in the seconds range, has been suggested to display time-of-day as well as wake dependent fluctuations due to circadian and sleep-homeostatic changes to the rate at which an ...
Aritake, Sayaka   +7 more
core   +2 more sources

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