Prevalence of OSA Risk and Bruxism in Children With Autism Spectrum Disorders
ABSTRACT Children with autism spectrum disorder (ASD) often present with sleep disorders, including obstructive sleep apnea (OSA), a condition characterized by upper airway obstruction during sleep. Bruxism has been recently described as being associated with OSA.
Anna Alessandri‐Bonetti +5 more
wiley +1 more source
A Predictive Model of Risk Factors for Conversion From Major Depressive Disorder to Bipolar Disorder Based on Clinical Characteristics and Circadian Rhythm Gene Polymorphisms [PDF]
Zhi Ping Xu +11 more
openalex +1 more source
Protocol of the SOMNIA project : an observational study to create a neurophysiological database for advanced clinical sleep monitoring [PDF]
Introduction Polysomnography (PSG) is the primary tool for sleep monitoring and the diagnosis of sleep disorders. Recent advances in signal analysis make it possible to reveal more information from this rich data source.
Arsenali, Bruno +16 more
core +2 more sources
Aims Fazamorexant is a dual orexin receptor antagonist being developed for the treatment of insomnia. This study aims to determine the dose‐exposure‐response relationship of single‐dose fazamorexant vs. zolpidem in young adult and elderly healthy Chinese volunteers. Methods This single‐centre, randomized, double‐blind, double‐dummy, placebo‐ and active‐
Chen Xia +3 more
wiley +1 more source
Randomized trial of polychromatic blue-enriched light for circadian phase shifting, melatonin suppression, and alerting responses. [PDF]
Wavelength comparisons have indicated that circadian phase-shifting and enhancement of subjective and EEG-correlates of alertness have a higher sensitivity to short wavelength visible light.
Ayers, M. +12 more
core +2 more sources
Recent studies have suggested that there are certain pathophysiological relationships between bipolar disorder (BD) and circadian rhythm dysfunction. However, apparently no studies have clarified the prevalence of circadian rhythm sleep-wake disorders ...
Y. Takaesu +6 more
semanticscholar +1 more source
Abstract Recurrent seizures, the hallmark of epilepsy, are influenced by rhythms operating over multiple timescales. Chronobiology is the study of biological timing that aims to explain temporal patterns of events like seizures. Fueled by recent advances in genetics, computational modeling, and device engineering, the chronobiology of epilepsy is now a
Maxime O. Baud +4 more
wiley +1 more source
Seizure forecasting with epilepsy cycles: On the causality of forecasting pipelines
Abstract Objective Seizure risk is modulated by multiscale brain rhythms. Previous studies using cycles in electroencephalography, heart rate, and wearable data suggest the possibility of forecasting seizures days in advance. However, they commonly rely on methods requiring (days of) information from time points beyond the moment of forecast (noncausal
Hongliu Yang +6 more
wiley +1 more source
Assaying locomotor activity to study circadian rhythms and sleep parameters in Drosophila. [PDF]
Most life forms exhibit daily rhythms in cellular, physiological and behavioral phenomena that are driven by endogenous circadian (≡24 hr) pacemakers or clocks. Malfunctions in the human circadian system are associated with numerous diseases or disorders.
Chiu, Joanna C +4 more
core +3 more sources
Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus +7 more
wiley +1 more source

