Results 51 to 60 of about 176,535 (378)

Recent advances in modulators of circadian rhythms: an update and perspective

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
Circadian rhythm is a universal life phenomenon that plays an important role in maintaining the multiple physiological functions and regulating the adaptability to internal and external environments of flora and fauna.
Shenzhen Huang, Xinwei Jiao, Dingli Lu, Xiaoting Pei, Di Qi, Zhijie Li   +5 more
doaj   +1 more source

Circadian rhythms and hormonal homeostasis: Pathophysiological implications [PDF]

, 2017
Over recent years, a deeper comprehension of the molecular mechanisms that control biological clocks and circadian rhythms has been achieved. In fact, many studies have contributed to unravelling the importance of the molecular clock for the regulation ...
Bruscalupi, Giovannella, Gnocchi, Davide
core   +2 more sources

Mood Prediction of Patients With Mood Disorders by Machine Learning Using Passive Digital Phenotypes Based on the Circadian Rhythm: Prospective Observational Cohort Study

Journal of Medical Internet Research, 2019
Background Virtually, all organisms on Earth have their own circadian rhythm, and humans are no exception. Circadian rhythms are associated with various human states, especially mood disorders, and disturbance of the circadian rhythm is known to be very ...
C. Cho, Taek Lee, Min-Gwan Kim, H. In, L. Kim, Heon-Jeong Lee   +5 more
semanticscholar   +1 more source

Research progress on correlation between circadian rhythm disturbance and work-related musculoskeletal disorders

环境与职业医学
Circadian rhythm refers to the 24-hour periodic changes in behavior, physiology, and molecular processes in the human body. Disruptions to the circadian rhythm not only affect mental health but are also associated with various metabolic disorders ...
Lichong LAI, Pinyue TAO, Dejing FAN, Shuyu LU, Jie PENG, Huiqiao HUANG   +5 more
doaj   +1 more source

Circadian rhythm and neurodegenerative disorders

Brain Science Advances, 2020
The circadian clock controls daily rhythms in animal physiology, metabolism, and behavior, such as the sleep‐wake cycle. Disruption of circadian rhythms has been revealed in many diseases including neurodegenerative disorders.
Michelle Werdann, Yong Zhang
doaj   +1 more source

Advances in the Study of Circadian Genes in Non-Small Cell Lung Cancer

Integrative Cancer Therapies, 2022
Circadian genes regulate several physiological functions such as circadian rhythm and metabolism and participate in the cytogenesis and progression of various malignancies.
Hao Zhang MMed, Renwang Liu MD, Bo Zhang MD, Huandong Huo MMed, Zuoqing Song MD   +4 more
doaj   +1 more source

A PERIOD3 variant causes a circadian phenotype and is associated with a seasonal mood trait. [PDF]

, 2016
In humans, the connection between sleep and mood has long been recognized, although direct molecular evidence is lacking. We identified two rare variants in the circadian clock gene PERIOD3 (PER3-P415A/H417R) in humans with familial advanced sleep phase ...
Fu, Ying-Hui, Hirano, Arisa, Hsu, Pei-Ken, Jones, Christopher R, Kaasik, Krista, Lin, Shu-Ting, McMahon, Thomas, Nishino, Seiji, Okuro, Masashi, Ptáček, Louis J, Saigoh, Kazumasa, Saigoh, Noriko, Sakai, Noriaki, Xu, Ying, Yamazaki, Maya, Zhang, Luoying   +15 more
core   +1 more source

Use of Actigraphy for the Evaluation of Sleep Disorders and Circadian Rhythm Sleep-Wake Disorders: An American Academy of Sleep Medicine Clinical Practice Guideline

Journal of Clinical Sleep Medicine (JCSM), 2018
The purpose of this guideline is to establish clinical practice recommendations for the use of actigraphy in adult and pediatric patients with suspected or diagnosed sleep disorders or circadian rhythm sleep-wake disorders.
Michael T. Smith, C. McCrae, Joseph Cheung, Jennifer L Martin, C. Harrod, Jonathan L. Heald, K. Carden   +6 more
semanticscholar   +1 more source

DA-JC1 improves learning and memory by antagonizing Aβ31–35-induced circadian rhythm disorder

Molecular Brain, 2019
Studies have shown that a normal circadian rhythm is crucial to learning and memory. Circadian rhythm disturbances that occur at early stages of Alzheimer’s disease (AD) aggravate the progression of the disease and further reduce learning and memory in ...
Li Wang, Rui Zhang, Xiaohong Hou, Changtu Wang, Shuai Guo, Na Ning, Cong Sun, Yuan Yuan, Lin Li, Christian Hölscher, Xiaohui Wang   +10 more
doaj   +1 more source

Circadian Rhythm Abnormalities in Parkinson's Disease from Humans to Flies and Back [PDF]

, 2018
Clinical and research studies have suggested a link between Parkinson\u2019s disease (PD) and alterations in the circadian clock. Drosophila melanogaster may represent a useful model to study the relationship between the circadian clock and PD.
Bisaglia, Marco, De Lazzari, Federica, Sandrelli, Federica, Zordan, Mauro Agostino   +3 more
core   +1 more source