Results 121 to 130 of about 11,759,117 (298)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Jixie chuandong, 2017 The flexure hinge is the most basic compliant structure,the compliance is the most important performance parameter. The combined compliance method is proposed fully based upon the structure characteristic of the flexure hinge.
Guan Lixin, Liu Qingling
doaj
Workmen's Circle collection, undated, 1903-1993.
Collection consists of material from the administration, services, individual branches, and schools of the Workmen's Circle. The majority of the collection are publications of the Workmen's Circle relating to conventions and education.
Workmen's Circle. +1 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
The Circle Method and Pointwise Ergodic Theorems
Volume 4: Invited Lectures: Sections 5–8The purpose of this article is to discuss the circle method and its quantitative role in understanding pointwise almost everywhere convergence phenomena for polynomial ergodic averaging operators. Specifically, we will use the circle method to illustrate that pointwise almost everywhere convergence and norm convergence in ergodic theory can have ...
openaire +2 more sources
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Vienna Circle Institute Yearbook [PDF]
The series is published by Springer under the auspices of the Society for the Advancement of the Scientific Worl Conception, based in Vienna (Istitute Vienna Circle, University of Vienna)
GALAVOTTI, MARIA CARLA
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