Results 51 to 60 of about 1,741,837 (286)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Near-Solar-Circle Method for Determination of the Galactic Constants

open access: yes, 2011
We propose a method to determine the galactic constants R_0 (distance to the Galactic Center) and V_0 (rotation velocity of the Sun) from measurements of distances, radial velocities and proper motions of objects near the solar circle.
Matsui, M.   +3 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Iris Localization Using Circle And Fuzzy Circle Detection Method

open access: yes, 2012
{"references": ["Chiara. Braghin, \"Biometric Authentication\", Technical report, 2000,\nhttp://citeseer.ist.psu.edu/436492.html.", "NSTC Subcommittee, \"Iris Recognition\", Aug. 2006,\nhttp://www.biometricscatalog.org/NSTCSubcommittee.", "J. Daugman, \"How iris recognition works\", IEEE Trans. Circuits Syst.\nVideo Technol., vol. 14, no. 1, pp. 21-30,
Marzieh. Savoj, S. Amirhassan. Monadjemi
openaire   +1 more source

Great Circle Navigation with Vectorial Methods [PDF]

open access: yesJournal of Navigation, 2010
The present paper is concerned with the solution of a series of practical problems relevant to great circle navigation, including the determination of the true course at any point on the great circle route and the determination of the lateral deviation from a desired great circle route.
NASTRO V, TANCREDI, Urbano
openaire   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Fast recognition of characteristic targets in spatial rendezvous and docking posture measurement

open access: yesDianzi Jishu Yingyong, 2019
In the space rendezvous and docking, real-time measurement of the position and attitude between the visual sensor on the tracking spacecraft and the characteristic target on the target spacecraft is needed, and the premise is to quickly and accurately ...
Luo Xiaoyi   +5 more
doaj   +1 more source

Improved algebraic methods for circle fitting

open access: yesElectronic Journal of Statistics, 2009
Inspired by the circle fitting algorithm "Hyper" of Al- Sharadqah and Chernov (1), which eliminates the second order "essential bias" that excludes terms of O( 2 /N 2 ), we extend their analysis and show that by a small modification the second order bias can be eliminated com- pletely. By numerical experiments, we show that this results in better per-
Rangarajan, Prasanna, Kanatani, Kenichi
openaire   +2 more sources

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