Results 81 to 90 of about 93,203 (297)

Proof Complexity Lower Bounds from Algebraic Circuit Complexity [PDF]

, 2021
We give upper and lower bounds on the power of subsystems of the Ideal Proof System (IPS), the algebraic proof system recently proposed by Grochow and Pitassi (J.
Avi Wigderson, Wigderson, Avi, Iddo Tzameret, Tzameret, Iddo, Michael A. Forbes, Shpilka, Amir, Amir Shpilka, Forbes, Michael A   +7 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Complexity and Idiosyncrasy at the Federal Circuit

, 2018
As a specialized intermediate appellate court with exclusive jurisdiction over all U.S. patent appeals, the Federal Circuit wields extraordinary power over the development of the language of patent law. Scholars theorize that the Federal Circuit’s isolation causes it to speak to a narrow audience (the specialized patent bar and sophisticated members of
Cahoy, Daniel R., Oswald, Lynda J.
openaire   +2 more sources

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Vertically stacked, low-voltage organic ternary logic circuits including nonvolatile floating-gate memory transistors

Nature Communications, 2022
High-density information processing without increasing the circuit complexity is highly desired in electronics. Here, Im et al. demonstrate a low-voltage organic ternary logic circuit vertically integrated with the nonvolatile flash memory, increasing ...
Junhwan Choi, Changhyeon Lee, Chungryeol Lee, Hongkeun Park, Seung Min Lee, Chang-Hyun Kim, Hocheon Yoo, Sung Gap Im   +7 more
doaj   +1 more source

Complexity of circuit intersection in graphs

Discrete Mathematics, 1995
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Aviezri S. Fraenkel, Martin Loebl
openaire   +1 more source

Circuit Complexity of Mixed States [PDF]

, 2021
Quantum information has produced fresh insights into foundational questions about the AdS/CFT correspondence. One fascinating concept, which has captured increasing attention, is quantum circuit complexity.
Ruan, Shan-Ming
core  

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source