Results 111 to 120 of about 5,709,499 (335)

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Prediction of vortex shedding from circular and noncircular bodies in supersonic flow [PDF]

open access: yes
An engineering prediction method and associated computer code NOZVTX to predict nose vortex shedding from circular and noncircular bodies in supersonic flow at angles of attack and roll are presented.
Mendenhall, M. R., Perkins, S. C., Jr.
core   +1 more source

Vortex-induced vibration of a square-section cylinder with incidence angle variation [PDF]

open access: yes, 2010
Vortex-induced vibration (VIV) occurs when vortex shedding from a body results in fluctuating forces that, in turn, cause the body to vibrate. This can result in undesired large-amplitude vibrations leading to structural damage or catastrophic failure ...
Lo Jacono, David   +3 more
core  

TREX1, a predator for treating MSI‐H tumors?

open access: yesMolecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya   +2 more
wiley   +1 more source

Foreign Bodies Simulating a Congenital Palatal Fistula and Vascular Anomaly

open access: yesCase Reports in Dentistry, 2015
Foreign bodies embedded in the palate are uncommon findings and may occasionally mimic oral lesions. In the majority of the cases, foreign body embedment in the palate happens in infants and children who are unable to give history.
Mekonen Eshete   +4 more
doaj   +1 more source

Unsteady Newton-Busemann flow theory. Part 2: Bodies of revolution [PDF]

open access: yes
Newtonian flow theory for unsteady flow past oscillating bodies of revolution at very high Mach numbers is completed by adding a centrifugal force correction to the impact pressures.
Hui, W. H., Tobak, M.
core   +1 more source

Chaos in Planar, Circular, Restricted Three-Body Problem

open access: yesApplied Mathematics, 2013
In this article we analyze the motion of a test particle of a planar, circular, restricted three-body problem in resonance, using the Kustaanheimo-Stiefel formalism. We show that a good qualitative description of the motion can be reduced to three simple equations for semi-major axis, eccentricity and resonance angle.
openaire   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Application of local linearization and the transonic equivalence rule to the flow about slender analytic bodies at Mach numbers near 1.0 [PDF]

open access: yes
The local linearization method for axisymmetric flow is combined with the transonic equivalence rule to calculate pressure distribution on slender bodies at free-stream Mach numbers from .8 to 1.2.
Muraca, R. J., Tyson, R. W.
core   +1 more source

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