Results 111 to 120 of about 467,200 (296)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Application of local linearization and the transonic equivalence rule to the flow about slender analytic bodies at Mach numbers near 1.0 [PDF]
The local linearization method for axisymmetric flow is combined with the transonic equivalence rule to calculate pressure distribution on slender bodies at free-stream Mach numbers from .8 to 1.2.
Muraca, R. J., Tyson, R. W.
core +1 more source
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Rigorous derivation of the formula for the buckling load in axially compressed circular cylindrical shells [PDF]
, 2014 The goal of this paper is to apply the recently developed theory of buckling of arbitrary slender bodies to a tractable yet non-trivial example of buckling in axially compressed circular cylindrical shells, regarded as three-dimensional hyperelastic ...
Grabovsky, Yury, Harutyunyan, Davit
core +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Prediction of subsonic vortex shedding from forebodies with chines [PDF]
An engineering prediction method and associated computer code VTXCHN to predict nose vortex shedding from circular and noncircular forebodies with sharp chine edges in subsonic flow at angles of attack and roll are presented.
Lesieutre, Daniel J. +1 more
core +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
The investigation of the flow about general fuselage shapes at high angles of attack [PDF]
Water tunnel visualization of the flow about bodies at high angles of attack was done.
Clarkson, M. H.
core +1 more source
Periodic solutions for circular restricted \(N+1\)-body problems
, 2013 Summary: For circular restricted \(N+1\)-body problems, we study the motion of a sufficiently small mass point (called the zero mass point) in the plane of \(N\) equal masses located at the vertices of a regular polygon. By using variational minimizing methods, for some \(N\), we prove the existence of the noncollision periodic solution for the zero ...
Zhao, Xiaoxiao, Li, Wei, Wang, Peng
openaire +2 more sources
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source