Results 141 to 150 of about 467,200 (296)
A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large‐scale comparison of US‐based assessment with histologic markers of skin fibrosis has not been reported. We evaluated US‐based skin assessments for their face validity (differentiation between involved SSc and healthy
Ruhani Desai +12 more
wiley +1 more source
Diffusion‐Weighted Imaging for the Evaluation of the Sacroiliac Joint in Pediatric Patients
Arthritis Care &Research, EarlyView.Objective Maturational signal in the sacroiliac joint (SIJ) of skeletally immature youth is often misinterpreted as inflammation. Diagnostic tools that improve specificity are greatly needed. Apparent diffusion coefficient (ADC) values from diffusion‐weighted imaging (DWI), when used with standard imaging, may enhance diagnostic accuracy.
Michael L. Francavilla +6 more
wiley +1 more source
A two parameter survey of periodic orbits in the restricted problem of three bodies [PDF]
Within the context of the restricted problem of three bodies the effects caused by varying the mass ratio of the primaries and the eccentricity of their orbits, upon periodic orbits of the infinitesimal mass which are numerical continuations of circular ...
Shelus, P. J.
core +1 more source
The co-circular central configurations of the 5 body problem
, 2015 Chenciner in 2001 asked: Is the regular n-gon with equal masses the unique central configuration such that all the bodies lie on a circle, and the center of mass coincides with the center of the circle? This question has a positive answer for n = 3. Hampton in 2003 proved that also this question has a positive answer for n = 4.
Llibre, Jaume, Valls, Clàudia
openaire +4 more sources
Arthritis Care &Research, EarlyView.Objective Antinuclear antibodies (ANAs) are present at high titers in 2% of the general population, but their clinical significance in individuals without an autoimmune (AI) disease is not known. We tested the hypothesis that the presence of a high ANA titer in non‐AI conditions is associated with disease.
Matthew Chung +7 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner +14 more
wiley +1 more source
Effect of underwing aft-mounted nacelles on the longitudinal aerodynamic characteristics of a high-wing transport airplane [PDF]
As part of a propulsion/airframe integration program, tests were conducted in the Langley 16-Foot Transonic Tunnel to determine the longitudinal aerodynamic effects of installing flow through engine nacelles in the aft underwing position of a high wing ...
Abeyounis, W. K., Patterson, J. C., Jr.
core +1 more source
Arthritis Care &Research, EarlyView.Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
Numerical solution of potential flow about arbitrary 2-dimensional multiple bodies [PDF]
A procedure for the finite-difference numerical solution of the lifting potential flow about any number of arbitrarily shaped bodies is given. The solution is based on a technique of automatic numerical generation of a curvilinear coordinate system ...
Thames, F. C., Thompson, J. F.
core +1 more source