Results 121 to 130 of about 1,297,074 (297)

Circular Design Futures

open access: yesThe Design Journal, 2017
As The Design Journal celebrates its 20-year anniversary, the Textiles Environment Design (TED) research group at University of the Arts London marks a similar milestone moment. In this paper, I reflect on the journey I have taken as a member of this staff cluster of textile tutors and practicing industry designers.
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Exploring Circularity Toolkits for SMEs Learning Ecosystems.

open access: yesInteraction Design and Architecture(s)
This research explores the role of Circular Design and education in facilitating the transition to a Circular Economy for SMEs and start-ups.
Massimo Bianchini   +2 more
doaj   +1 more source

Parametric Design and Motion Simulation Analysis of Non-circular Gear Planetary Gear Train

open access: yesJixie chuandong, 2021
Non-circular gear planetary gear train is the core component of non-circular gear hydraulic motor, and its pitch curve design is the key to the overall structure design.
Yongping Liu   +3 more
doaj  

A 2.4-GHz, 2.2-W, 2-V fully-integrated CMOS circular-geometry active-transformer power amplifier [PDF]

open access: yes, 2001
A 2.4-GHz, 2.2-W, 2-V fully integrated circular geometry power amplifier with 50 Ω input and output matching is fabricated using 2.5V, 0.35 pm CMOS transistors. It can also produce 450mW using a 1V supply. Harmonic suppression is 64dB or better.
Aoki, Ichiro   +3 more
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Circular Design Strategies

open access: yes, 2023
Le istanze della transizione verso gli obiettivi della Nuova strategia industriale europea richiedono un passaggio dalla logica della minimizzazione a quella di modelli rivolu- zionari di consumo e produzione che vanno oltre al concetto di sostenibilità.
Badalucco, L., Fortuna, P.
openaire   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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