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Dynamics of extrachromosomal circular DNA in rice [PDF]
Nature CommunicationsThe genome’s dynamic nature, exemplified by elements like extrachromosomal circular DNA (eccDNA), is crucial for biodiversity and adaptation. Yet, the role of eccDNA in plants, particularly rice, remains underexplored.
Jundong Zhuang +10 more
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Extrachromosomal circular DNA: a new potential role in cancer progression
Journal of Translational Medicine, 2021 Extrachromosomal circular DNA (eccDNA) is considered a circular DNA molecule that exists widely in nature and is independent of conventional chromosomes. eccDNA can be divided into small polydispersed circular DNA (spcDNA), telomeric circles (t-circles),
Tianyi Wang +3 more
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Journal of Hematology & Oncology, 2020 Extrachromosomal circular DNA was recently found to be particularly abundant in multiple human cancer cells, although its frequency varies among different tumor types.
Yuanliang Yan +7 more
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New Insights on Molecular Mechanism of Hepatitis B Virus Covalently Closed Circular DNA Formation
Cells, 2020 The chronic factor of the Hepatitis B Virus (HBV), specifically the covalently closed circular DNA (cccDNA), is a highly stable and active viral episomal genome established in the livers of chronic hepatitis B patients as a constant source of disease ...
Alexander L. Marchetti, Haitao Guo
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Extrachromosomal Circular DNA: Category, Biogenesis, Recognition, and Functions
Frontiers in Veterinary Science, 2021 Extrachromosomal circular DNA (eccDNA), existing as double-stranded circular DNA, is derived and free from chromosomes. It is common in eukaryotes but has a strong heterogeneity in count, length, and origin.
Xiukai Cao +6 more
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Expression of HIV from a 1-LTR circular DNA in the absence of integration [PDF]
RetrovirologyBackground Like all retroviruses, two kinds of viral DNA are present in the nucleus of HIV-infected cells: integrated DNA and a pool of unintegrated DNA containing linear and circular forms. For the most part, it has been difficult to examine the role of
Corrado Gurgo +4 more
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Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells [PDF]
Journal of Visualized Experiments, 2016 Extrachromosomal circular DNAs (eccDNAs) are common genetic elements in Saccharomyces cerevisiae and are reported in other eukaryotes as well. EccDNAs contribute to genetic variation among somatic cells in multicellular organisms and to evolution of ...
Bojsen, Rasmus Kenneth +5 more
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Detection of HBV Covalently Closed Circular DNA
Viruses, 2017 Chronic hepatitis B virus (HBV) infection affects approximately 240 million people worldwide and remains a serious public health concern because its complete cure is impossible with current treatments.
Xiaoling Li +3 more
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The extrachromosomal circular DNA atlas of aged and young mouse brains [PDF]
Scientific DataExtrachromosomal circular DNA (eccDNA) refers to a distinct class of circular DNA molecules that exist independently from linear chromosomal DNA. Extensive evidence has firmly established the significant involvement of eccDNA in cancer initiation ...
Xiaoning Hong +8 more
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Diverse Small Circular DNA Viruses Identified in an American Wigeon Fecal Sample [PDF]
MicroorganismsAmerican wigeons (Mareca americana) are waterfowls that are widely distributed throughout North America. Research of viruses associated with American wigeons has been limited to orthomyxoviruses, coronaviruses, and circoviruses.
Diego Olivo +4 more
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