Results 11 to 20 of about 3,020,470 (372)

Differences in sequences between HBV-relaxed circular DNA and covalently closed circular DNA [PDF]

Emerging Microbes and Infections, 2017
The hepatitis B virus (HBV) genome exists in two forms: circular covalently closed DNA (cccDNA) and relaxed circular DNA (RCDNA). Here, we investigated the presence of differences in the sequences of both forms in paired samples of serum and liver tissue.
Magda Rybicka, Anna Woziwodzka, Tomasz Romanowski, Piotr Stalke, Marcin Dręczewski, Krzysztof Piotr Bielawski   +5 more
doaj   +5 more sources

Denaturation of Circular DNA: Supercoil Mechanism

Physical Review E, 2011
The denaturation transition which takes place in circular DNA is analyzed by extending the Poland-Scheraga model to include the winding degrees of freedom.
Alkan Kabakçoğlu, Amir Bar, David Mukamel, H. Hiasa, L. Lewin, M. Abramowitz, Y. Kafri   +6 more
core   +6 more sources

Circular DNA tumor viruses make circular RNAs [PDF]

Proceedings of the National Academy of Sciences, 2018
Significance Circular RNAs (circRNAs) play critical physiologic functions, but it is not known whether human DNA viruses express circRNAs. We surveyed Epstein−Barr virus (EBV) and Kaposi’s sarcoma herpesvirus (KSHV) tumors and cell lines, and found ...
T. Toptan, Bizunesh Abere, M. Nalesnik, S. Swerdlow, S. Ranganathan, Nara Lee, K. Shair, P. Moore, Yuan Chang   +8 more
semanticscholar   +3 more sources

Deciphering extrachromosomal circular DNA in Arabidopsis

Computational and Structural Biotechnology Journal, 2021
Extrachromosomal circular DNA (eccDNA) is independent of the chromosome and exists in many eukaryotes. However, the nature and origin of eccDNA in plants remains unclear.
Keyi Wang, Hui Tian, Lequn Wang, Lin Wang, Yacong Tan, Ziting Zhang, Kai Sun, Meng Yin, Qinggong Wei, Baohua Guo, Jinyu Han, Peiru Zhang, Han Li, Yulong Liu, Hongwei Zhao, Xiaoyong Sun   +15 more
doaj   +3 more sources

Circularity of yeast mitochondrial DNA. [PDF]

Proceedings of the National Academy of Sciences, 1968
Charlotte J. Avers, Foster E. Billheimer, Hans‐Peter Hoffmann, Richard M. Pauli   +3 more
openalex   +5 more sources

Extrachromosomal circular DNA: biogenesis, structure, functions and diseases

Signal Transduction and Targeted Therapy, 2022
Extrachromosomal circular DNA (eccDNA), ranging in size from tens to millions of base pairs, is independent of conventional chromosomes. Recently, eccDNAs have been considered an unanticipated major source of somatic rearrangements, contributing to ...
Ludi Yang, R. Jia, T. Ge, S. Ge, A. Zhuang, P. Chai, Xianqun Fan   +6 more
semanticscholar   +1 more source

Detection and Validation of Circular DNA Fragments Using Nanopore Sequencing

Frontiers in Genetics, 2022
Occurrence of extra-chromosomal circular DNA is a phenomenon frequently observed in tumor cells, and the presence of such DNA has been recognized as a marker of adverse outcome across cancer types.
Alicia Isabell Tüns, Till Hartmann, Simon Magin, Rocío Chamorro González, Rocío Chamorro González, Rocío Chamorro González, Rocío Chamorro González, Rocío Chamorro González, Anton George Henssen, Anton George Henssen, Anton George Henssen, Anton George Henssen, Anton George Henssen, Sven Rahmann, Alexander Schramm, Johannes Köster   +15 more
doaj   +1 more source

Extrachromosomal Circular DNA (eccDNA): From Chaos to Function

Frontiers in Cell and Developmental Biology, 2022
Extrachromosomal circular DNA (eccDNA) is a type of double-stranded circular DNA that is derived and free from chromosomes. It has a strong heterogeneity in sequence, length, and origin and has been identified in both normal and cancer cells.
Shanru Zuo, Yihu Yi, Chen Wang, Xueguang Li, Ming H Zhou, Qiyao Peng, Junhua Zhou, Yide Yang, Quanyuan He   +8 more
semanticscholar   +1 more source

Role of circular RNAs in DNA repair

RNA Biology
Circular RNAs (circRNAs) exhibit a wide range of activities that allow them to participate in numerous cellular processes and make them relevant in a variety of diseases.
Francisco Alejandro Lagunas-Rangel
doaj   +3 more sources

Extrachromosomal circular DNA (eccDNA): an emerging star in cancer

Biomarker Research, 2022
Extrachromosomal circular DNA (eccDNA) is defined as a type of circular DNA that exists widely in nature and is independent of chromosomes. EccDNA has attracted the attention of researchers due to its broad, random distribution, complex biogenesis and ...
Ruomeng Li, Ying Wang, Jing Li, Xikun Zhou   +3 more
semanticscholar   +1 more source