Results 231 to 240 of about 208,265 (305)

Insight into the Internal Structure of Biogenic, Synthetic and Geological Apatite by Electron Microscopy and X‐Ray Scattering

Advanced Functional Materials, EarlyView.
Apatite occurs in many forms in nature, e.g. in teeth and geological minerals. Internally, biological apatite contains nanocrystals that are also found in synthetically prepared calcium phosphate nanoparticles which are used in biomedicine, e.g. for gene and drug delivery and for bone regeneration. Abstract Calcium phosphate is the inorganic component (
Kathrin Kostka, Oleg Prymak, Kateryna Loza, Matthias Epple   +3 more
wiley   +1 more source

Rapid and Sensitive Detection of RNA Viruses through Imaging of Marker Molecules Derived from Designed Circular DNA Probes. [PDF]

Small Methods
Jang YH, Kim T, Hong SJ, Kim SY, Hwang H, Kim S, Kang SA, Won N, Kim D, Kim MJ, Chong YP, Jang S, Jo K, Lim KI.   +13 more
europepmc   +1 more source

Microsatellite break-induced replication generates highly mutagenized extrachromosomal circular DNAs [PDF]

Rujuta Yashodhan Gadgil, S. Dean Rider, Resha Shrestha, Venicia Alhawach, David C. Hitch, Michael Leffak   +5 more
openalex   +1 more source

Integrative Approaches for DNA Sequence‐Controlled Functional Materials

Advanced Functional Materials, EarlyView.
DNA is emerging as a programmable building block for functional materials with applications in biomimicry, biochemical, and mechanical information processing. The integration of simulations, experiments, and machine learning is explored as a means to bridge DNA sequences with macroscopic material properties, highlighting current advances and providing ...
Aaron Gadzekpo, Ewa Anna Oprzeska‐Zingrebe, Mariana Kozlowska, Lennart Hilbert, Iliya D. Stoev   +4 more
wiley   +1 more source

DNA‐Templated 2D Heterostructures as Phototriggered Dynamic Nanohybrids: From Releasing Molecular Loads to Controlling Enzyme Biocatalytic Function

Advanced Functional Materials, EarlyView.
DNA strands are employed both as dynamic linkers and nanoscale templates for the integration of Ag2S nanoparticles on MoS2, which in turn imparted photothermal responsiveness; this feature permits the selective cargo (fluorophore, quantum dots or an enzyme) release from the MoS2 surface in response to local heat induced by light irradiation.
Kai Chen, Haosen Miao, Weiying Hong, Matteo Palma   +3 more
wiley   +1 more source

Unveiling the mysteries of extrachromosomal circular DNA: from generation to clinical relevance in human cancers and health. [PDF]

Mol Cancer
Wang Z, Yu J, Zhu W, Hong X, Xu Z, Mao S, Huang L, Han P, He C, Song C, Xiang X.   +10 more
europepmc   +1 more source

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

Extrachromosomal circular DNA orchestrates genome heterogeneity in urothelial bladder carcinoma. [PDF]

Theranostics
Lv W, Pan X, Han P, Wu S, Zeng Y, Wang Q, Guo L, Xu M, Qi Y, Deng L, Xu Z, Li C, Yu T, Cui X, Teng H, Xiang C, Tan H, Li Y, Liang N, Tao H, Gao Q, Yu G, Mi J, Xu F, Gong B, Shi L, Wang T, Yang H, Dong W, Bolund L, Lin L, Wang W, Li H, Huang J, Lin C, Luo Y.   +35 more
europepmc   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Chronic Hepatitis B Genotype C Mouse Model with Persistent Covalently Closed Circular DNA. [PDF]

Viruses
Seo DH, Hur W, Won J, Han JW, Yoon SK, Bae S, Kim KH, Sung PS.   +7 more
europepmc   +1 more source