Results 91 to 100 of about 174,880 (353)
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
More about Q-ball with elliptical orbit
Q-balls formed from the Affleck-Dine field have rich cosmological implications and have been extensively studied from both theoretical and simulational approaches.
Fuminori Hasegawa +2 more
doaj +1 more source
Accretion within the innermost stable circular orbit: analytical thermodynamic solutions in the adiabatic limit [PDF]
Andrew Mummery, Steven A. Balbus
openalex +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Analysis of perturbation solutions of varied thrust trajectories Final report [PDF]
Perturbation solution analysis of vehicle transfer from one planetary circular orbit to circular orbit around another planet using low thrust ...
Auelmann, R. R., Lane, P. T.
core +1 more source
The imprint of non-linearities in the propagation of gravitational waves --- the tail effect --- is responsible for new spin contributions to the energy flux and orbital phasing of spinning black hole binaries.
Blanchet, Luc +3 more
core +3 more sources
Inspirals from the innermost stable circular orbit of Kerr black holes: Exact solutions and universal radial flow [PDF]
Andrew Mummery, Steven A. Balbus
openalex +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Type I Outbursts in Low-eccentricity Be/X-Ray Binaries
Type I outbursts in Be/X-ray binaries are usually associated with the eccentricity of the binary orbit. The neutron star accretes gas from the outer parts of the decretion disk around the Be star at each periastron passage. However, this mechanism cannot
Franchini, Alessia, Martin, Rebecca G.
core +2 more sources

