Results 151 to 160 of about 1,797,821 (330)

Photomodulating RNA cleavage using photolabile circular antisense oligodeoxynucleotides [PDF]

, 2010
Xinjing Tang, Meng Su, Lili Yu, Cong Lv, Jie Wang, Zhongjin Li   +5 more
openalex   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Analysis of the regulation of undecaprenyl diphosphate dephosphorylation in Escherichia coli

FEBS Open Bio, EarlyView.
BacA, PgpB, and YbjG phosphatases are involved in undecaprenyl phosphate (C55P) synthesis in Escherichia coli. We analyzed the lipid contents and the gene expression in the gene‐disruption strains. Undecaprenyl diphosphate (C55PP) level increased in the bacA, ybjG double‐disruption strain, but C55P levels were similar in all strains.
Tomotaka Jitsukawa, Yasushi Shigeri, Shingo Fujisaki   +2 more
wiley   +1 more source

Circ2Traits: a comprehensive database for circular RNA potentially associated with disease and traits [PDF]

, 2013
Suman Ghosal, Shaoli Das, Rituparno Sen, Piyali Basak, Jayprokas Chakrabarti   +4 more
openalex   +1 more source

Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis

Molecules and Cells, 2017
I. Legnini, Gaia Di Timoteo, F. Rossi, M. Morlando, Francesca Briganti, O. Sthandier, A. Fatica, Tiziana Santini, A. Andronache, M. Wade, Pietro Laneve, N. Rajewsky, I. Bozzoni   +12 more
semanticscholar   +1 more source

Liver‐specific lncRNAs associated with liver cancers

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina, Roman K. Makarchenko, Maria P. Rubtsova, Olga A. Dontsova   +3 more
wiley   +1 more source

The Expanding Repertoire of Circular RNAs [PDF]

, 2013
Paul N. Valdmanis, Mark A. Kay
openalex   +1 more source

The Landscape of Circular RNA in Cancer

Cell, 2019
Josh N. Vo, M. Cieslik, Yajia Zhang, S. Shukla, Lanbo Xiao, Yuping Zhang, Yi-Mi Wu, S. Dhanasekaran, Carl G. Engelke, Xuhong Cao, D. Robinson, A. Nesvizhskii, A. Chinnaiyan   +12 more
semanticscholar   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source