Results 131 to 140 of about 1,315,460 (260)
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Analysis of circZNF609: a multifunctional circular RNA with oncogenic properties
reservedCircular RNAs (circRNAs) are a peculiar class of stable RNAs that have a covalently closed loop structure originated from a noncanonical splicing event (back-splicing), characterized by the lack of 5’ and 3’ ends.
CONTE, EMMA
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Juntos : campaña Ciudades del Caribe Circular
, 2023 ¿Cómo enfrentamos la problemática de contaminación por plásticos? Lo hacemos juntos, todos los sectores: gobiernos centrales, gobiernos locales, iniciativa privada y sociedad civil.
Proyecto Caribe Circular
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Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Frontiers in Molecular MedicineN6-methyladenosine (m6A) is the best-studied post-transcriptional RNA modification. It refers to the methylation in the N6 position. M6A exists universally from viruses to mammalian cells and is highly abundant in RNA polymerase II-transcribed, protein ...
Heedoo Lee +3 more
doaj +1 more source
Circular on Economic Utilization and Efficient Delivery of Telephone Services in the Public Service
, 2010 Your attention is drawn to Circular No. OP/CAB/15/SA (2) of 26th August 2003 which provided guidelines on the above subject. The current circular provides for officers in Job Group "N" and above, and leaves out some officers performing key functions in ...
Executive Office of the President
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FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Activation of influenza virus RNA polymerase by the 5' and 3' terminal duplex of genomic RNA [PDF]
, 2003 The current model for influenza virus mRNA transcription involves the sequential interaction of the viral polymerase with the 5'- and 3'-ends of vRNA, with each RNA-protein interaction triggering a polymerase function necessary for cap-primed ...
Tiley, Laurence +3 more
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