Results 1 to 10 of about 36,533 (268)
The functions and clinical significance of circRNAs in hematological malignancies
Journal of Hematology and Oncology, 2020 With covalently closed circular structures, circular RNAs (circRNAs) were once misinterpreted as by-products of mRNA splicing. Being abundant, stable, highly conserved, and tissue-specific, circRNAs are recently identified as a type of regulatory RNAs ...
Xiangxiang Zhou, Haiying Wang
exaly +3 more sources
CIRCULAR RNA – miRNA MEDIATED INTERACTION IN MYOCARDIAL INFARCTION [PDF]
Journal of IMAB, 2021 Circular RNA (circRNAs) belong to the long non-coding RNA family, but unlike the linear RNA in circular RNA, the 3’ and 5’ end in the RNA molecule are joined together, forming their circular structure.
Yordanka Doneva +5 more
doaj +1 more source
Functions of CircRNAs in osteogenic differentiation [PDF]
Yixue xinzhi zazhi, 2021 CircRNAs are a special class of non-coding RNA (ncRNA) molecules. They have a closed circular structure and are formed by reverse splicing by non-classical splicing methods. They coexist in highly differentiated eukaryotes.
Hui-Xian DONG +2 more
doaj +1 more source
Cellular and molecular basis of thyroid autoimmunity
European Thyroid Journal, 2023 Autoimmune thyroid disease (AITD) is the most common human autoimmune disease. The two major clinical manifestations of AITD are Graves’ disease and Hashimoto’s thyroiditis (HT).
Joanna Bogusławska +3 more
doaj +1 more source
Differential expression of circRNAs of testes with high and low sperm motility in Yili geese
Frontiers in Genetics, 2022 The aim of this study was to explore the potential biological function of circular RNAs (circRNAs) in the sperm motility traits of Xinjiang Yili geese, and to provide a reference for analyzing the mechanism of regulation of Yili geese sperm motility. The
Yingping Wu +8 more
doaj +1 more source
Accentuating CircRNA-miRNA-Transcription Factors Axis: A Conundrum in Cancer Research
Frontiers in Pharmacology, 2022 Circular RNAs (circRNAs) are the newly uncovered class of non-coding RNAs being cognized as profound regulators of gene expression in developmental and disease biology.
Deepti Singh +3 more
doaj +1 more source
Closing the circle : current state and perspectives of circular RNA databases [PDF]
, 2021 Circular RNAs (circRNAs) are covalently closed RNA molecules that have been linked to various diseases, including cancer. However, a precise function and working mechanism are lacking for the larger majority.
Vandesompele, Jo +2 more
core +1 more source
Biomolecules, 2020 Heart failure (HF) is a deadly disease that is difficult to accurately diagnose. Circular RNAs (circRNAs) are a novel class of noncoding RNAs that might play important roles in many cardiovascular diseases.
Yeying Sun +8 more
doaj +1 more source
Zhongguo shuxue zazhi, 2023 Objective To investigate the effect of transfusion-transmitted Zika virus (ZIKV) on the expression of circular RNA (hsa_circ_0000290) and the role of hsa_circ_0000290 in ZIKV replication.
Lan KANG +6 more
doaj +1 more source
Identification and characterization of circular RNAs in Qinchuan cattle testis [PDF]
Royal Society Open Science, 2018 Circular RNA (circRNA) is a new class of non-coding RNA that has recently attracted researchers' interest. Studies have demonstrated that circRNA can function as microRNA sponges or competing endogenous RNAs.
Yuan Gao +9 more
doaj +1 more source